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GI Pathology

GI Pathology: In gastrointestinal (GI) pathology, IHC is critical for diagnosing cancers like colorectal adenocarcinoma, gastric cancer, and gastrointestinal stromal tumors (GISTs). Markers like CD117, CD34, and MUC2 help distinguish between tumor types, while mismatch repair (MMR) proteins can indicate hereditary conditions like Lynch syndrome.

	target	type	reactivity	applications
6014	AFP	mouse monoclonal (C3)	human	IHC
6024	Arginase-1	rabbit monoclonal (ZR368)	human	IHC
6045	CA19-9	mouse monoclonal (121SLE)	human	IHC
6055	CD117	rabbit monoclonal (ZR424)	human	IHC
6056	CD117	mouse monoclonal (ZM321)	human	IHC
6119	CDX2	rabbit monoclonal (ZR215)	human	IHC
6120	CEA-M	mouse monoclonal (CEA31)	human	IHC
6121	CEA-P	rabbit monoclonal (Poly)	human	IHC
6122	CEACAM5	rabbit monoclonal (ZR370)	human	IHC
6125	Claudin 18.2	rabbit monoclonal (ZR451)	human	IHC
6129	CPA1	rabbit monoclonal (ZR450)	human	IHC
6142	Cytokeratin 20	mouse monoclonal (ZM42)	human	IHC
6143	Cytokeratin 20	mouse monoclonal (Ks20.8)	human	IHC
6144	Cytokeratin 20	rabbit monoclonal (ZR429)	human	IHC
6160	DOG-1	mouse monoclonal (DOG1.1)	human	IHC
6161	DOG-1	rabbit monoclonal (ZR146)	human	IHC
6162	DPC4 (SMAD4)	rabbit monoclonal (ZR392)	human	IHC
6163	DPC4 (SMAD4)	mouse monoclonal (B-8)	human	IHC
6198	Glutamine synthetase	mouse monoclonal (ZM377)	human	IHC
6426	Glutamine synthetase	rabbit monoclonal (ZR431)	human	IHC
6200	Glypican 3	rabbit monoclonal (ZR405)	human	IHC
6201	Glypican 3	mouse monoclonal (1G12)	human	IHC
6202	Glypican 3	mouse monoclonal (ZM138)	human	IHC
6211	HepPar-1	mouse monoclonal (OCH1E5)	human	IHC
6217	HSP70	rabbit monoclonal (ZR152)	human	IHC
6227	IMP-3	rabbit monoclonal (EP286)	human	IHC
6257	MLH-1	mouse monoclonal (G168-728)	human	IHC
6258	MLH-1	rabbit monoclonal (ZR347)	human	IHC
6260	MSH-2	mouse monoclonal (G219-1129)	human	IHC
6430	MSH-2	rabbit monoclonal (ZR260)	human	IHC
6262	MSH-6	mouse monoclonal (ZM99)	human	IHC
6263	MSH-6	rabbit monoclonal (ZR342)	human	IHC
6266	MUC-2	mouse monoclonal (Ccp58)	human	IHC
6267	MUC-2	rabbit monoclonal (ZR175)	human	IHC
6269	MUC-5AC	rabbit monoclonal (ZR19)	human	IHC
6270	MUC-5AC	mouse monoclonal (ZM148)	human	IHC
6433	PMS-2	rabbit monoclonal (ZR317)	human	IHC
6361	SATB2	rabbit monoclonal (ZR167)	human	IHC
6402	Villin	rabbit monoclonal (ZR155)	human	IHC

IHC with antibody [6198] : Formalin-fixed, paraffin-embedded human liver stained with anti-glutamine synthetase antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of hepatocytes around a central vein.

IHC with antibody [6426] : Formalin-fixed, paraffin-embedded human liver stained with anti-glutamine synthetase antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of hepatocytes around a central vein.

IHC with antibody [6200] : Human hepatocellular carcinoma stained with anti-GPC3 antibody using peroxidase-conjugate and DAB chromogen. Note membranous and granular cytoplasmic staining of tumor cells.

ICC