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Vimentin antibodies

9046rabbitmonoclonalIgGhuman mouse ratWBICCIHC

Vimentin, a key protein constituent of the intermediate filament cytoskeleton, plays a pivotal role in maintaining cellular integrity and structure. In research, vimentin has become a valuable biomarker due to its tissue-specific expression and involvement in various cellular processes. Immunohistochemical analysis of vimentin has been extensively utilized to identify and characterize mesenchymal cells, such as fibroblasts, endothelial cells, and immune cells, aiding in the study of tissue development, wound healing, and cancer progression. Additionally, vimentin has been linked to epithelial-mesenchymal transition (EMT), a critical process implicated in embryonic development and metastasis. Antibodies targeting vimentin have proven to be indispensable tools in both research and diagnostic applications, facilitating the detection and quantification of vimentin in different cell types and tissues. Furthermore, efforts to develop vimentin-targeting therapies for cancer treatment have shown promise, as vimentin’s involvement in EMT and tumor progression make it a potential therapeutic target for limiting cancer metastasis. As research continues to unveil vimentin’s diverse roles in cellular physiology and disease, its relevance as a biomarker and therapeutic target remains an exciting area of investigation.