vimentin antibodies

Vimentin is a type III intermediate filament protein that is a key component of the cytoskeleton, primarily expressed in mesenchymal cells. It plays a critical role in maintaining cellular integrity, supporting organelle positioning, and facilitating processes such as migration, wound healing, and cell signaling. Vimentin is also associated with epithelial-mesenchymal transition (EMT), a process involved in cancer metastasis and tissue regeneration, making it an important marker in studies of cell differentiation and cancer progression.In Western blotting (WB), vimentin is frequently used to evaluate mesenchymal cells and track changes associated with EMT. The vimentin antibodies offered on your website can also be used in immunofluorescence (IF) and immunohistochemistry (IHC), enabling the visualization of cytoskeletal structures in various tissues. These applications are particularly valuable in cancer research, where vimentin serves as a marker for invasive and metastatic cell types, as well as in studies of developmental biology and fibrosis.Due to its broad expression in mesenchymal cells and its involvement in cellular remodeling and motility, vimentin is a crucial marker for investigating cytoskeletal dynamics, cell plasticity, and pathological conditions such as cancer, fibrosis, and tissue regeneration