Immunohistochemistry (IHC) : Human colon carcinoma stained with anti-CA19-9 antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of tumor cells.

mouse anti-CA19-9 monoclonal antibody (121SLE) 6045

Price range: $160.00 through $528.00

Antibody summary

Mouse monoclonal to CA19-9
Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Reacts with: Human
Isotype:IgM
Control: Colon carcinoma
Visualization: Cytoplasmic
0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted

available sizes

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SKU: 6045parent Categories: antibody, Zeta IHC antibodies Tags: anatomy, CA19-9, GI Pathology

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgM
clonality	monoclonal
concentration	concentrate, predilute
applications	IHC
reactivity	human
available size	0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

mouse anti-CA19-9 monoclonal antibody 121SLE 6045

antibody

Tested applications IHC
Recommended dilutions Concentrated 1:100-200
Application Notes Positive control: Colon carcinoma
Immunogen Precipitin lines obtained after immuno-diffusion using MAb 116-NS-19-9 and mucins isolated from an ovarian cyst of a Lewis A+B-patient (0Le)
Size and concentration 7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form liquid
Storage Instructions 2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity affinity purified
Clonality monoclonal
Isotype IgM
Compatible secondaries goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486 goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854 goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706 goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control Mouse monoclonal IgM - Isotype Control

target relevance
CA19
Protein names Carbohydrate antigen 19-9
Alternative names CA19-9, Cancer antigen 19-9, Sialyl-Lewis A, sLea, Sialylated Lewis A antigen
Function CA19-9 represents the sialyl-Lewis A carbohydrate epitope. It participates in selectin-mediated cell adhesion and is frequently overexpressed in malignant epithelial tissues.
Involvement in disease Elevated CA19-9 levels are associated with pancreatic cancer, cholangiocarcinoma, colorectal cancer, gastric cancer, and other gastrointestinal malignancies.
Description CA19-9 is a tumor-associated carbohydrate antigen corresponding to the sialyl-Lewis A glycan structure. It is expressed on glycoproteins and glycolipids and is widely used as a biomarker in gastrointestinal malignancies.
Related entities relationship: related_to; entity: Lewis A antigen relationship: related_to; entity: Sialyl-Lewis X relationship: associated_with; entity: MUC1 relationship: associated_with; entity: MUC5AC
Keywords Glycan, Carbohydrate antigen, Pancreatic cancer, Gastrointestinal cancer, Tumor biomarker
Structure CA19-9 corresponds to the sialyl-Lewis A (sLea) carbohydrate epitope, a sialylated glycan structure present on glycoproteins and glycolipids.
Function CA19-9 participates in selectin-mediated cell adhesion and is frequently expressed by malignant epithelial cells.
Clinical relevance CA19-9 is the most widely used serum biomarker for pancreatic cancer and is also elevated in several other gastrointestinal malignancies and some benign inflammatory diseases.
Expression The CA19-9 epitope can be present on multiple glycoproteins and glycolipids and is therefore not associated with a single protein target.
Research relevance CA19-9 is extensively used in cancer biomarker studies, pathology, tumor biology, and assay development.

Data

Human colon carcinoma stained with anti-CA19-9 antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of tumor cells.

FAQ & Publications

Frequently Asked Questions

What are the recommended storage conditions for the mouse anti-CA19-9 monoclonal antibody (121SLE) 6045?

For short-term storage, keep the antibody at 2-8°C. For long-term storage, it should be kept at -20°C. Avoid repeated freeze/thaw cycles to maintain antibody stability.

Which species does the mouse anti-CA19-9 monoclonal antibody (121SLE) 6045 react with, and what is its recommended application?

This monoclonal antibody reacts specifically with human tissues. It is suitable for immunohistochemistry (IHC) applications, particularly using formalin-fixed, paraffin-embedded human tissue samples.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.