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LAMP1 antibodies
Lysosomal-associated membrane protein 1 (LAMP1) is a key protein found on the membrane of lysosomes, playing a crucial role in lysosomal function and cellular homeostasis. LAMP1 is involved in maintaining lysosomal integrity, supporting autophagy, and facilitating cellular degradation processes. Due to its widespread expression in various cell types and tissues, LAMP1 serves as an important marker for identifying lysosomes and studying autophagic activity and lysosomal function.In Western blotting (WB), LAMP1 is commonly used to monitor lysosomal activity and track changes in response to cellular stress, disease states, or experimental treatments. Antibodies for LAMP1 available on your website can also be used in immunofluorescence (IF) and immunohistochemistry (IHC), allowing for the precise visualization of lysosomes within cells and tissues. This helps researchers investigate lysosomal distribution, function, and dysfunction, which is particularly relevant in studies of neurodegenerative diseases, cancer, and metabolic disorders.LAMP1 is an essential tool in cell biology research, providing valuable insights into lysosome-related processes such as autophagy, cellular waste removal, and the response to various pathological conditions.
target | type | reactivity | applications | ||||
---|---|---|---|---|---|---|---|
9022 | LAMP1 | mouse monoclonal | human | WB ICC IHC |
WB with antibody [9022] : LAMP-1 Antibody (H4A3): Near-infrared western blot analysis of LAMP-1 expression in MDA-MB-231 (A), K-562 (B), HT-1080 (C) and JAR (D) whole cell lysates.
WB with antibody [9022] : LAMP-1 Antibody (H4A3) Alexa Fluor® 546:AF546. Direct fluorescent western blot analysis of LAMP-1 expression in U-937 (A) and ECV304 (B) whole cell lysates.
IHC with antibody [9022] : LAMP-1 Antibody (H4A3): Immunoperoxidase staining of formalin fixed, paraffin-embedded human esophagus tissue showing cytoplasmic staining of squamous epithelial cells.