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LAMP1 antibodies
species | type | applications | ||||||
---|---|---|---|---|---|---|---|---|
9022 | mouse | monoclonal | IgG1 | human | WB | ICC | IHC |
The LAMP1 protein, also known as lysosomal-associated membrane protein 1, has garnered substantial attention in scientific research due to its crucial role in lysosomal function and cellular processes. As a transmembrane protein primarily localized to the lysosomal membrane, LAMP1 plays a key role in maintaining lysosomal integrity, fusion, and trafficking, contributing to lysosomal biogenesis and autophagy. Its presence on the lysosomal surface also facilitates endocytosis and phagocytosis, vital processes for nutrient uptake and pathogen clearance. Researchers have extensively studied LAMP1 to gain insights into lysosomal biology, lysosomal storage disorders, and autophagic processes, as its aberrant expression or function has been linked to various diseases, including cancer, neurodegenerative disorders, and infectious diseases. Additionally, LAMP1 serves as a valuable marker for identifying and tracking lysosomes and autophagosomes in live-cell imaging studies, enabling a deeper understanding of intracellular trafficking events.