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BrdU antibodies


5-bromo-2′-deoxyuridine (BrdU) has proven to be a valuable marker for studying cell proliferation in various research fields, including cancer biology, developmental biology, and neuroscience. BrdU is a thymidine analog that incorporates into the DNA of actively dividing cells during the S phase of the cell cycle. As a result, it becomes integrated into newly synthesized DNA strands, making it a specific and reliable indicator of cell proliferation. By administering BrdU to experimental models, researchers can trace and identify proliferating cells over specific timeframes, providing valuable insights into cell turnover rates, tissue regeneration, and growth patterns. Utilizing BrdU in immunohistochemistry or flow cytometry allows scientists to visualize and quantify the proportion of dividing cells in tissues or cultures, aiding in the assessment of cell proliferation rates and the effects of various experimental treatments or genetic manipulations.