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Breast Pathology

Breast Pathology: In breast cancer diagnosis, IHC is essential for identifying hormone receptor status, such as estrogen and progesterone receptors, and HER2/neu expression. These markers not only help in classifying breast cancer subtypes but also guide treatment decisions, such as the use of hormone therapies or HER2-targeted treatments. IHC is also used to detect prognostic markers, providing insights into disease progression.



Human breast stained with Keratin 14 using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of myoepithelial cells.
IHC with antibody [6135] : Human breast stained with Keratin 14 using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of myoepithelial cells.
Formalin-fixed, paraffin-embedded human squamous cell carcinoma stained with CK14 using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of squamous cells
IHC with antibody [6136] : Formalin-fixed, paraffin-embedded human squamous cell carcinoma stained with CK14 using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of squamous cells
Formalin-fixed paraffin-embedded human breast lobular anti-E-Cadherin antibody using peroxidase-conjugate and DAB chromogen. Note the strong membranous staining of ductal cells (top), whereas tumor cells show weak cytoplasmic staining.
IHC with antibody [6164] : Formalin-fixed paraffin-embedded human breast lobular anti-E-Cadherin antibody using peroxidase-conjugate and DAB chromogen. Note the strong membranous staining of ductal cells (top), whereas tumor cells show weak cytoplasmic staining.
ICC