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Cytomegalovirus IgM ELISA Kit ESR109M

$325.00

Summary

  • Virion/Serion Diagnostic Kit for research use (RUO)
  • Cytomegalovirus IgM ELISA Kit
  • Suitable for IgM detection
  • Ready-to-use
  • 96 tests
Weight1 lbs
Dimensions9 × 5 × 2 in
target

Cytomegalovirus reactive IgM

species reactivity

Cytomegalovirus

applications

ELISA

assay type

Indirect & quantitative

available sizes

96 tests

Available product – Cytomegalovirus IgM ELISA Kit ESR109M

kit
Assay type
Indirect ELISA
Research area
Infectious Disease
Sample type
Serum, plasma, whole blood
Notes
Pretreatment of samples with RF-Absorbent (Z200) is recommended for use with IgM ELISA kits to eliminate presence of sample rheumatoid factors and possible false negative results.
Components
Break apart microtiter test strips each with antigen coated single wells8 x 12 (96 Total)
Standard serum (ready-to-use)2 x 2 mL
Negative control serum (ready-to-use)2 mL
Anti-human-IgM-conjugate (ready-to-use)13 mL
Washing solution concentrate (sufficient for 1000ml)33.3 mL
Dilution buffer2 x 50 mL
Stopping solution15 mL
Substrate (ready-to-use)13 mL
Quality control certificate with standard curve and evaluation table1
Storage
Store at 2-8°C.
Associated products
Cytomegalovirus Avidity Reagent (B109AVID)
Cytomegalovirus Antigen (BA109VS)
Cytomegalovirus IgG Control Serum (BC109G)
Cytomegalovirus IgM Control Serum (BC109M)
Cytomegalovirus IgG ELISA Kit (ESR109G)
Cytomegalovirus IgM ELISA Kit (ESR109M)
target relevance
Organism
Cytomegalovirus
Structure and strains
Cytomegalovirus (CMV) is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Betaherpesvirinae. Humans and other primates serve as natural hosts. The 11 species in this genus include human betaherpesvirus 5 (HCMV, human cytomegalovirus, HHV-5), which is the species that infects humans. Diseases associated with HHV-5 include mononucleosis and pneumonia, and congenital CMV in infants can lead to deafness and ambulatory problems.

In the medical literature, most mentions of CMV without further specification refer implicitly to human CMV. Human CMV is the most studied of all cytomegaloviruses.
Disease
Cytomegalovirus (CMV) is a human pathogenic DNA virus belonging to the herpes virus group. Primary infection may result from contact with saliva, genital secretions, urine and breast milk of infected persons, as well as from transfusions or transplantations.

Primary infections usually remain asymptomatic. Clinical manifestations vary considerably depending on age and immunocompetence ranging from localized infections to generalized diseases. Significant clinical diseases or death may follow infection of immunocompromized individuals. Reactivation in immunocompetent adults is usually asymptomatic but accompanied by virus secretion. In immunocompromized patients reactivation of CMV infections may result in clinically severe diseases. CMV infection is a major cause of complications in iatrogenic immunsuppression after organ transplantation and in HIV infected persons. CMV is the most important causative agent of congenital and postnatal infections. Primary infections as well as reactivations during pregnancy may result in fetopathy. The risk of fetal damage is higher in cases of primary infections than during reactivations.
Detection and diagnosis
The diagnosis of CMV infections is performed on the basis of clinical symptoms and medical examinations. For serological diagnosis immunoglobulin specific IgM and IgG ELISA and, when necessary, tests for avidity determination are recommended.

Data

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




pmidtitleauthorscitation

Protocols

relevant to this product
ESR109M protocol

Documents

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