Cytomegalovirus Antigen BA109VS

$941.00

Summary

Virion/Serion Immunologics Antigen for research use (RUO)
Cytomegalovirus (CMV) Antigen, recombinant
Suitable for detection of IgA, IgG & IgM antibodies in ELISA
Lot specific concentration, specified in mg/mL
1 mg

SKU: BA109VS Category: Infectious disease proteins Tags: antigen, Cytomegalovirus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Cytomegalovirus
species reactivity	Cytomegalovirus
applications	ELISA
assay type	Indirect & quantitative
available size	1 mg

Cytomegalovirus Antigen BA109VS

kit
Research area Infectious Disease
Storage Store at -65°C or lower. Avoid repeated freeze-thaw cycles. Sonicate before use. 10 years from date of manufacture (under recommended storage conditions).
Form liquid
Associated products Cytomegalovirus Avidity Reagent (B109AVID) Cytomegalovirus Antigen (BA109VS) Cytomegalovirus Avidity Control(BR109AVID) Cytomegalovirus Antigen (BA109VS) Cytomegalovirus IgG Control Serum (BC109G) Cytomegalovirus IgM Control Serum (BC109M) Cytomegalovirus IgG ELISA Kit (ESR109G) Cytomegalovirus IgM ELISA Kit (ESR109M)

target relevance
Cytomegalovirus (CMV)
Description Virus that causes cytomegalovirus infection and congenital CMV disease
Structure Cytomegalovirus (CMV), also known as Human herpesvirus 5 (HHV-5), is an enveloped, double-stranded DNA virus belonging to the genus Cytomegalovirus within the family Herpesviridae. The virus possesses an icosahedral capsid surrounded by a protein tegument and a lipid envelope containing multiple glycoproteins involved in host cell entry. CMV has one of the largest genomes among human viruses and is capable of infecting a wide variety of cell types including epithelial cells, endothelial cells, fibroblasts, monocytes, and leukocytes. Following primary infection, CMV establishes lifelong latency, primarily within cells of the myeloid lineage, and may periodically reactivate, particularly in immunocompromised individuals. CMV is widely distributed throughout the world, and a large proportion of adults show evidence of prior infection.
Diagnosis The diagnosis of cytomegalovirus infection is performed through serological, molecular, and virological methods. Detection of CMV-specific IgM and IgG antibodies by ELISA or other immunoassays is commonly used to determine recent or past infection. Molecular methods such as quantitative polymerase chain reaction (PCR) are highly sensitive and are widely used to detect and monitor CMV DNA in blood, urine, saliva, cerebrospinal fluid, and other clinical specimens. Antigenemia assays and viral culture may also be employed in selected clinical settings. In pregnant women and immunocompromised patients, laboratory testing is particularly important for assessing active infection, viral load, and risk of disease progression.
Symptoms Most cytomegalovirus infections in healthy individuals are asymptomatic or cause mild, self-limiting illness resembling infectious mononucleosis, characterized by fever, fatigue, malaise, sore throat, lymphadenopathy, and muscle aches. Following primary infection, the virus remains latent and may reactivate later in life. In immunocompromised individuals, including transplant recipients, cancer patients, and people with advanced HIV infection, CMV can cause severe disease involving the lungs, liver, gastrointestinal tract, retina, and central nervous system. Congenital CMV infection is a major cause of birth defects and may result in hearing loss, vision impairment, developmental delays, microcephaly, seizures, and other neurological complications. CMV remains one of the most significant opportunistic viral pathogens worldwide.

Data

FAQ & Publications

Frequently Asked Questions

What types of antibodies can be detected using the Cytomegalovirus Antigen BA109VS in ELISA assays?

The Cytomegalovirus Antigen BA109VS is suitable for detecting IgA, IgG, and IgM antibodies in ELISA assays.

What are the recommended storage conditions for maintaining the stability of Cytomegalovirus Antigen BA109VS?

The antigen should be stored at -65°C or lower, avoiding repeated freeze-thaw cycles, and sonicated before use to maintain its stability. Under these conditions, it is stable for up to 10 years from the date of manufacture.

Which species does the Cytomegalovirus Antigen BA109VS react with for research applications?

The Cytomegalovirus Antigen BA109VS is reactive with Cytomegalovirus species, specifically human cytomegalovirus (HCMV), which is the species that infects humans.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.