| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| target | Candida albicans reactive IgM |
| species reactivity | Candida albicans |
| applications | ELISA |
| assay type | Indirect & quantitative |
| available sizes | 96 tests |
Candida albicans IgM ELISA kit-SERION classic ESR117M
$398.00
RF-Absorbent Z200 for use with IgM ELISA kits
Did you know that RF Absorbent Z200 is recommended for the removal of IgM rheumatoid factors from serum and plasma samples prior to the detection of pathogen-specific IgM? Consider adding it to your cart for improved signal specificity. For more details, please refer to the IgM ELISA kit protocol.
- Virion/Serion Diagnostic Kit for research use (RUO)
- Candida albicans IgM ELISA Kit
- Suitable for IgM detection
- Ready-to-use
- 96 tests
Candida albicans IgM ELISA Kit ESR117M
| kit | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Assay type Indirect ELISA | ||||||||||||||||||
| Research area Infectious Disease | ||||||||||||||||||
| Sample type Serum, plasma, whole blood | ||||||||||||||||||
| Notes Pretreatment of samples with RF-Absorbent (Z200) is recommended for use with IgM ELISA kits to eliminate presence of sample rheumatoid factors and possible false negative results. | ||||||||||||||||||
Components
| ||||||||||||||||||
| Storage Store at 2-8°C. | ||||||||||||||||||
| Associated products Candida albicans Antigen (BA117VS) Candida Antigen Assay Control (BC200) Candida albicans IgA Control Serum (BC117A) Candida albicans IgG Control Serum (BC117G) Candida albicans IgM Control Serum (BC117M) Candida albicans IgA ELISA Kit (ESR117A) Candida albicans IgG ELISA Kit (ESR117G) Candida albicans IgM ELISA Kit (ESR117M) Candida Antigen Detection ELISA Kit (ESR200) |
| target relevance |
|---|
| Candida albicans |
| Description Fungus that causes candidiasis and opportunistic fungal infections |
| Structure Candida albicans is a dimorphic yeast-like fungus belonging to the family Debaryomycetaceae and is the most common cause of human candidiasis. The organism normally colonizes the oral cavity, gastrointestinal tract, genitourinary tract, and skin of healthy individuals as part of the normal microbiota. Candida albicans exhibits remarkable morphological flexibility and can transition between yeast, pseudohyphal, and true hyphal forms depending on environmental conditions. This ability to undergo morphologic switching is an important virulence factor that facilitates tissue invasion, immune evasion, and biofilm formation. C. albicans is an opportunistic pathogen that typically causes disease when host defenses are compromised, microbiota balance is disrupted, or anatomical barriers are breached. It is one of the most common fungal pathogens responsible for both superficial mucosal infections and invasive systemic disease. |
| Diagnosis The diagnosis of Candida albicans infection is performed through microbiological, microscopic, molecular, and serological methods. Direct microscopic examination of clinical specimens using potassium hydroxide preparations, Gram staining, or fungal stains may reveal budding yeast cells, pseudohyphae, and hyphae. Culture on fungal media remains a standard diagnostic method and allows species identification and antifungal susceptibility testing. Molecular techniques such as polymerase chain reaction (PCR) provide rapid and sensitive detection of Candida DNA. In cases of invasive candidiasis, blood cultures, beta-D-glucan assays, antigen detection tests, and advanced molecular diagnostics may assist in diagnosis. Histopathological examination of affected tissues can demonstrate fungal invasion and support the diagnosis of invasive disease. |
| Symptoms Candida albicans infections range from mild superficial disease to life-threatening systemic infections. Oral candidiasis (thrush) commonly presents with white plaques on the tongue and oral mucosa, soreness, and difficulty swallowing. Vulvovaginal candidiasis is characterized by itching, irritation, redness, burning, and abnormal vaginal discharge. Cutaneous candidiasis may cause erythematous, moist, and pruritic lesions, particularly in warm skin folds. Invasive candidiasis occurs when the organism enters the bloodstream or deep tissues and may present with persistent fever, chills, sepsis, organ dysfunction, and failure to respond to antibacterial therapy. Patients at highest risk include immunocompromised individuals, transplant recipients, cancer patients, premature infants, and critically ill hospitalized patients. Untreated invasive infection may disseminate to the kidneys, liver, spleen, heart, eyes, brain, and other organs, resulting in significant morbidity and mortality. |
Data
FAQ & Publications
Frequently Asked Questions
What types of samples are compatible with the Candida albicans IgM ELISA Kit ESR117M?
The Candida albicans IgM ELISA Kit ESR117M is compatible with serum, plasma, and whole blood samples for the detection of Candida albicans reactive IgM antibodies.
How should the Candida albicans IgM ELISA Kit ESR117M be stored to maintain its stability?
The kit components should be stored at 2-8°C to ensure proper stability and performance.
Is there any recommended pretreatment for samples before using this IgM ELISA kit?
Yes, pretreatment of samples with RF-Absorbent Z200 is recommended to remove IgM rheumatoid factors, which may cause false negative results in the assay.
What is the assay format and principle used in the Candida albicans IgM ELISA Kit ESR117M?
This kit uses an indirect and quantitative ELISA assay format designed for the detection of Candida albicans specific IgM antibodies.
How many tests are included in one Candida albicans IgM ELISA Kit ESR117M package?
Each kit contains reagents sufficient for performing 96 tests using break-apart microtiter test strips with antigen-coated wells.
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.
Protocols
| relevant to this product |
|---|
| ESR117M protocol |
Only logged in customers who have purchased this product may leave a review.
Reviews
There are no reviews yet.