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Cytomegalovirus IgG ELISA kit-SERION classic ESR109G

$355.00

Summary

Virion/Serion Diagnostic Kit for research use (RUO)
Cytomegalovirus (CMV) IgG ELISA Kit
Suitable for IgG detection
Ready-to-use
96 tests

SKU: ESR109G Category: Virion/Serion kits Tags: Cytomegalovirus, ELISA, IgG

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Cytomegalovirus reactive IgG
species reactivity	Cytomegalovirus
applications	ELISA
assay type	Indirect & quantitative
available sizes	96 tests

Cytomegalovirus IgG ELISA Kit ESR109G

Assay type
Indirect ELISA

Research area
Infectious Disease

Sample type
Serum, plasma, whole blood

Components

Break apart microtiter test strips each with antigen coated single wells	8 x 12 (96 Total)
Standard serum (ready-to-use)	2 x 2 mL
Negative control serum (ready-to-use)	2 mL
Anti-human-IgG-conjugate (ready-to-use)	13 mL
Washing solution concentrate (sufficient for 1000ml)	33.3 mL
Dilution buffer	2 x 50 mL
Stopping solution	15 mL
Substrate (ready-to-use)	13 mL
Quality control certificate with standard curve and evaluation table	1

Storage
Store at 2-8°C.

Associated products
Cytomegalovirus Avidity Reagent (B109AVID)
Cytomegalovirus Antigen (BA109VS)
Cytomegalovirus Avidity Control(BR109AVID)
Cytomegalovirus Antigen (BA109VS)
Cytomegalovirus IgG Control Serum (BC109G)
Cytomegalovirus IgM Control Serum (BC109M)
Cytomegalovirus IgG ELISA Kit (ESR109G)
Cytomegalovirus IgM ELISA Kit (ESR109M)

target relevance

human antibody anti-Cytomegalovirus (CMV)

Cytomegalovirus (CMV)

Description
Virus that causes cytomegalovirus infection and congenital CMV disease

Structure
Cytomegalovirus (CMV), also known as Human herpesvirus 5 (HHV-5), is an enveloped, double-stranded DNA virus belonging to the genus Cytomegalovirus within the family Herpesviridae. The virus possesses an icosahedral capsid surrounded by a protein tegument and a lipid envelope containing multiple glycoproteins involved in host cell entry. CMV has one of the largest genomes among human viruses and is capable of infecting a wide variety of cell types including epithelial cells, endothelial cells, fibroblasts, monocytes, and leukocytes. Following primary infection, CMV establishes lifelong latency, primarily within cells of the myeloid lineage, and may periodically reactivate, particularly in immunocompromised individuals. CMV is widely distributed throughout the world, and a large proportion of adults show evidence of prior infection.

Diagnosis
The diagnosis of cytomegalovirus infection is performed through serological, molecular, and virological methods. Detection of CMV-specific IgM and IgG antibodies by ELISA or other immunoassays is commonly used to determine recent or past infection. Molecular methods such as quantitative polymerase chain reaction (PCR) are highly sensitive and are widely used to detect and monitor CMV DNA in blood, urine, saliva, cerebrospinal fluid, and other clinical specimens. Antigenemia assays and viral culture may also be employed in selected clinical settings. In pregnant women and immunocompromised patients, laboratory testing is particularly important for assessing active infection, viral load, and risk of disease progression.

Symptoms
Most cytomegalovirus infections in healthy individuals are asymptomatic or cause mild, self-limiting illness resembling infectious mononucleosis, characterized by fever, fatigue, malaise, sore throat, lymphadenopathy, and muscle aches. Following primary infection, the virus remains latent and may reactivate later in life. In immunocompromised individuals, including transplant recipients, cancer patients, and people with advanced HIV infection, CMV can cause severe disease involving the lungs, liver, gastrointestinal tract, retina, and central nervous system. Congenital CMV infection is a major cause of birth defects and may result in hearing loss, vision impairment, developmental delays, microcephaly, seizures, and other neurological complications. CMV remains one of the most significant opportunistic viral pathogens worldwide.

Data

FAQ & Publications

Frequently Asked Questions

What sample types are compatible with the Cytomegalovirus IgG ELISA Kit ESR109G?

The Cytomegalovirus IgG ELISA Kit ESR109G is compatible with serum, plasma, and whole blood samples for the detection of CMV reactive IgG.

How should the Cytomegalovirus IgG ELISA Kit ESR109G be stored to maintain its stability?

The kit should be stored at 2-8°C to ensure stability and optimal performance.

What components are included in the Cytomegalovirus IgG ELISA Kit ESR109G for assay performance?

The kit includes break apart microtiter test strips coated with antigen, standard serum, negative control serum, anti-human-IgG-conjugate, washing solution concentrate, dilution buffer, stopping solution, substrate, and a quality control certificate with standard curve and evaluation table.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
ESR109G protocol BR109AVID B109AVID

Documents

#
EP0168	Safety Data Sheet	QC certificate

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Cytomegalovirus IgG ELISA kit-SERION classic ESR109G

Data

FAQ & Publications

Protocols

Documents

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Reviews

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