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Coxsackievirus IgG ELISA kit-SERION classic ESR134G

$364.00

Summary

Virion/Serion Diagnostic Kit for research use (RUO)
Coxsackievirus IgG ELISA Kit
Suitable for IgG detection
Ready-to-use
96 tests

SKU: ESR134G Category: Virion/Serion kits Tags: Coxsackievirus, ELISA, IgG

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Coxsackievirus reactive IgG
species reactivity	Coxsackievirus (hand, foot, and mouth disease)
applications	ELISA
assay type	Indirect & quantitative
available sizes	96 tests

Coxsackievirus IgG ELISA Kit ESR134G

Assay type
Indirect ELISA

Research area
Infectious Disease

Sample type
Serum, plasma, whole blood

Components

Break apart microtiter test strips each with antigen coated single wells	8 x 12 (96 Total)
Standard serum (ready-to-use)	2 x 2 mL
Negative control serum (ready-to-use)	2 mL
Anti-human-IgG-conjugate (ready-to-use)	13 mL
Washing solution concentrate (sufficient for 1000ml)	33.3 mL
Dilution buffer	2 x 50 mL
Stopping solution	15 mL
Substrate (ready-to-use)	13 mL
Quality control certificate with standard curve and evaluation table	1

Storage
Store at 2-8°C.

Associated products
Coxsackievirus Antigen (BA134VS01)
Cocksackie IgA Virus Control Serum (BC134A)
Cocksackie IgG Virus Control Serum (BC134G)
Cocksackie IgM Virus Control Serum (BC134M)
Cocksackievirus IgA ELISA Kit (ESR134A)
Cocksackievirus IgG ELISA Kit (ESR134G)
Cocksackievirus IgM ELISA Kit (ESR134M)

target relevance

human antibody anti-Coxsackievirus

Coxsackievirus

Description
Virus that causes hand, foot and mouth disease, herpangina, myocarditis, and other enteroviral infections

Structure
Coxsackieviruses are non-enveloped, positive-sense, single-stranded RNA viruses belonging to the genus Enterovirus within the family Picornaviridae. The viruses possess an icosahedral capsid that protects the viral RNA genome and contributes to environmental stability. Coxsackieviruses are divided into Group A and Group B based on their pathogenic properties and biological characteristics. These viruses are transmitted primarily through the fecal-oral route, respiratory secretions, and direct contact with contaminated surfaces. Following infection, viral replication typically occurs in the gastrointestinal and respiratory tracts before dissemination to other tissues. Coxsackieviruses are distributed worldwide and are a common cause of childhood and adult infections, with outbreaks occurring periodically in communities, schools, and daycare settings.

Diagnosis
The diagnosis of Coxsackievirus infection is performed through molecular, virological, and serological methods. Reverse transcription polymerase chain reaction (RT-PCR) is the preferred diagnostic technique for detecting viral RNA in throat swabs, stool samples, cerebrospinal fluid, blood, and tissue specimens due to its high sensitivity and specificity. Viral culture may be used in specialized laboratories but has largely been replaced by molecular methods. Serological assays, including ELISA-based tests, can detect virus-specific antibodies and may be useful in epidemiological investigations or retrospective diagnosis. Clinical presentation and epidemiological context often play an important role in guiding diagnostic testing.

Symptoms
Coxsackievirus infections produce a wide spectrum of clinical manifestations ranging from mild febrile illness to severe systemic disease. Group A coxsackieviruses commonly cause hand, foot and mouth disease and herpangina, characterized by fever, sore throat, painful oral ulcers, and vesicular lesions on the hands and feet. Group B coxsackieviruses are frequently associated with pleurodynia, myocarditis, pericarditis, and viral meningitis. Additional symptoms may include headache, fatigue, muscle aches, abdominal pain, nausea, vomiting, and rash. While most infections are self-limiting and resolve without complications, severe disease can occur in neonates, immunocompromised individuals, and patients with cardiac involvement, potentially resulting in life-threatening complications.

Data

FAQ & Publications

Frequently Asked Questions

What sample types are compatible with the Coxsackievirus IgG ELISA Kit ESR134G for detecting IgG antibodies?

The Coxsackievirus IgG ELISA Kit ESR134G is compatible with serum, plasma, and whole blood samples for the detection of IgG antibodies.

How should the Coxsackievirus IgG ELISA Kit ESR134G be stored to maintain its integrity?

The kit should be stored at 2-8°C to preserve the quality of its components and ensure reliable assay performance.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
ESR134G protocol

Documents

#
EQ0001	Safety Data Sheet	QC certificate

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Coxsackievirus IgG ELISA kit-SERION classic ESR134G

Data

FAQ & Publications

Protocols

Documents

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Reviews

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