Coxsackievirus Antigen BA134VS01

$1,054.00

Summary

Virion/Serion Immunologics Antigen for research use (RUO)
Coxsackievirus Antigen, recombinant
Suitable for detection of IgA, IgG & IgM antibodies in ELISA
Lot specific concentration, specified in mg/mL
1 mg

SKU: BA134VS01 Category: Infectious disease proteins Tags: antigen, Coxsackievirus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Coxsackievirus
species reactivity	Coxsackievirus (hand, foot, and mouth disease)
applications	ELISA
assay type	Indirect & quantitative
available size	1 mg

Coxsackievirus Antigen BA134VS01

kit
Research area Infectious Disease
Storage Store at -65°C or lower. Avoid repeated freeze-thaw cycles. 10 years from date of manufacture (under recommended storage conditions).
Form liquid
Associated products Coxsackievirus Antigen (BA134VS01) Cocksackie IgA Virus Control Serum (BC134A) Cocksackie IgG Virus Control Serum (BC134G) Cocksackie IgM Virus Control Serum (BC134M) Cocksackievirus IgA ELISA Kit (ESR134A) Cocksackievirus IgG ELISA Kit (ESR134G) Cocksackievirus IgM ELISA Kit (ESR134M)

target relevance
Coxsackievirus
Description Virus that causes hand, foot and mouth disease, herpangina, myocarditis, and other enteroviral infections
Structure Coxsackieviruses are non-enveloped, positive-sense, single-stranded RNA viruses belonging to the genus Enterovirus within the family Picornaviridae. The viruses possess an icosahedral capsid that protects the viral RNA genome and contributes to environmental stability. Coxsackieviruses are divided into Group A and Group B based on their pathogenic properties and biological characteristics. These viruses are transmitted primarily through the fecal-oral route, respiratory secretions, and direct contact with contaminated surfaces. Following infection, viral replication typically occurs in the gastrointestinal and respiratory tracts before dissemination to other tissues. Coxsackieviruses are distributed worldwide and are a common cause of childhood and adult infections, with outbreaks occurring periodically in communities, schools, and daycare settings.
Diagnosis The diagnosis of Coxsackievirus infection is performed through molecular, virological, and serological methods. Reverse transcription polymerase chain reaction (RT-PCR) is the preferred diagnostic technique for detecting viral RNA in throat swabs, stool samples, cerebrospinal fluid, blood, and tissue specimens due to its high sensitivity and specificity. Viral culture may be used in specialized laboratories but has largely been replaced by molecular methods. Serological assays, including ELISA-based tests, can detect virus-specific antibodies and may be useful in epidemiological investigations or retrospective diagnosis. Clinical presentation and epidemiological context often play an important role in guiding diagnostic testing.
Symptoms Coxsackievirus infections produce a wide spectrum of clinical manifestations ranging from mild febrile illness to severe systemic disease. Group A coxsackieviruses commonly cause hand, foot and mouth disease and herpangina, characterized by fever, sore throat, painful oral ulcers, and vesicular lesions on the hands and feet. Group B coxsackieviruses are frequently associated with pleurodynia, myocarditis, pericarditis, and viral meningitis. Additional symptoms may include headache, fatigue, muscle aches, abdominal pain, nausea, vomiting, and rash. While most infections are self-limiting and resolve without complications, severe disease can occur in neonates, immunocompromised individuals, and patients with cardiac involvement, potentially resulting in life-threatening complications.

Data

FAQ & Publications

Frequently Asked Questions

What is the primary application of the Coxsackievirus Antigen BA134VS01?

The Coxsackievirus Antigen BA134VS01 is primarily used for detection of IgA, IgG, and IgM antibodies in ELISA assays, supporting indirect and quantitative analysis.

How should the Coxsackievirus Antigen BA134VS01 be stored to maintain its stability?

This antigen should be stored at -65°C or lower and should be protected from repeated freeze-thaw cycles to ensure stability, with a shelf life of 10 years from the date of manufacture under these recommended conditions.

Is the Coxsackievirus Antigen BA134VS01 suitable for detecting antibodies from multiple immunoglobulin classes?

Yes, the antigen is suitable for detecting antibodies of the IgA, IgG, and IgM classes in ELISA assays.

Does the Coxsackievirus Antigen BA134VS01 target a specific virus strain or group?

The antigen targets Coxsackievirus, which is part of the Enterovirus genus and is associated with diseases such as hand, foot, and mouth disease.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.