Coxsackie IgA Virus Control Serum BC134A

$94.00

Summary

Virion/Serion Diagnostic Kit Control for research use (RUO)
Coxsackie IgA Virus Control Serum
Applications: ELISA
IgA control serum
Ready-to-use; pre-diluted for SERION ELISA classic and SERION ELISA antigen assays
3 mL

SKU: BC134A Categories: control serum, Virion/Serion kits Tags: Coxsackievirus, ELISA control serum, IgA

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Coxsackie Virus reactive IgA
species reactivity	Coxsackievirus (hand, foot, and mouth disease)
applications	ELISA
assay type	Indirect & quantitative
available size	3 mL

Coxsackie IgA Virus Control Serum BC134A

kit
Research area Infectious Disease
Storage Store at 2-8°C.
Associated products Coxsackievirus Antigen (BA134VS01) Cocksackie IgA Virus Control Serum (BC134A) Cocksackie IgG Virus Control Serum (BC134G) Cocksackie IgM Virus Control Serum (BC134M) Cocksackievirus IgA ELISA Kit (ESR134A) Cocksackievirus IgG ELISA Kit (ESR134G) Cocksackievirus IgM ELISA Kit (ESR134M)

target relevance

human antibody anti-Coxsackievirus

Coxsackievirus

Description
Virus that causes hand, foot and mouth disease, herpangina, myocarditis, and other enteroviral infections

Structure
Coxsackieviruses are non-enveloped, positive-sense, single-stranded RNA viruses belonging to the genus Enterovirus within the family Picornaviridae. The viruses possess an icosahedral capsid that protects the viral RNA genome and contributes to environmental stability. Coxsackieviruses are divided into Group A and Group B based on their pathogenic properties and biological characteristics. These viruses are transmitted primarily through the fecal-oral route, respiratory secretions, and direct contact with contaminated surfaces. Following infection, viral replication typically occurs in the gastrointestinal and respiratory tracts before dissemination to other tissues. Coxsackieviruses are distributed worldwide and are a common cause of childhood and adult infections, with outbreaks occurring periodically in communities, schools, and daycare settings.

Diagnosis
The diagnosis of Coxsackievirus infection is performed through molecular, virological, and serological methods. Reverse transcription polymerase chain reaction (RT-PCR) is the preferred diagnostic technique for detecting viral RNA in throat swabs, stool samples, cerebrospinal fluid, blood, and tissue specimens due to its high sensitivity and specificity. Viral culture may be used in specialized laboratories but has largely been replaced by molecular methods. Serological assays, including ELISA-based tests, can detect virus-specific antibodies and may be useful in epidemiological investigations or retrospective diagnosis. Clinical presentation and epidemiological context often play an important role in guiding diagnostic testing.

Symptoms
Coxsackievirus infections produce a wide spectrum of clinical manifestations ranging from mild febrile illness to severe systemic disease. Group A coxsackieviruses commonly cause hand, foot and mouth disease and herpangina, characterized by fever, sore throat, painful oral ulcers, and vesicular lesions on the hands and feet. Group B coxsackieviruses are frequently associated with pleurodynia, myocarditis, pericarditis, and viral meningitis. Additional symptoms may include headache, fatigue, muscle aches, abdominal pain, nausea, vomiting, and rash. While most infections are self-limiting and resolve without complications, severe disease can occur in neonates, immunocompromised individuals, and patients with cardiac involvement, potentially resulting in life-threatening complications.

Data

FAQ & Publications

Frequently Asked Questions

What is the intended application of the Coxsackie IgA Virus Control Serum BC134A?

The Coxsackie IgA Virus Control Serum BC134A is designed for use as a control serum in ELISA assays, specifically indirect and quantitative ELISA methods.

How should the Coxsackie IgA Virus Control Serum BC134A be stored to ensure stability?

This control serum should be stored refrigerated at 2-8°C to maintain its stability and efficacy.

Is the Coxsackie IgA Virus Control Serum BC134A compatible with SERION ELISA kits?

Yes, the serum is ready-to-use and pre-diluted specifically for SERION ELISA classic and SERION ELISA antigen assays, ensuring compatibility with these kits.

Which viral target and antibody class does the Coxsackie IgA Virus Control Serum BC134A detect?

This control serum targets Coxsackie virus-reactive IgA antibodies, allowing for the detection of IgA responses to Coxsackievirus infections.

Publications

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We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
BC134A protocol

Documents

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Coxsackie IgA Virus Control Serum BC134A

Data

FAQ & Publications

Protocols

Documents

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Reviews

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