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Borrelia burgdorferi IgG ELISA Kit ESR121G

$334.00

Summary

  • Virion/Serion Diagnostic Kit for research use (RUO)
  • Borrelia burgdorferi IgG ELISA Kit
  • Suitable for IgG detection
  • Ready-to-use
  • 96 tests
Weight1 lbs
Dimensions9 × 5 × 2 in
target

Borrelia burgdorferi reactive IgG

species reactivity

Borrelia burgdorferi

applications

ELISA

assay type

Indirect & quantitative

available sizes

96 tests

Available product – Borrelia burgdorferi IgG ELISA Kit ESR121G

kit
Assay type
Indirect ELISA
Research area
Infectious Disease
Sample type
Serum, plasma, whole blood
Notes
Pretreatment of samples with RF-Absorbent (Z200) is recommended for use with IgM ELISA kits to eliminate presence of sample rheumatoid factors and possible false negative results.
Components
Break apart microtiter test strips each with antigen coated single wells8 x 12 (96 Total)
Standard serum (ready-to-use)2 x 2 mL
Negative control serum (ready-to-use)2 mL
Anti-human-IgG-conjugate (ready-to-use)13 mL
Washing solution concentrate (sufficient for 1000ml)33.3 mL
Dilution buffer2 x 50 mL
Stopping solution15 mL
Substrate (ready-to-use)13 mL
Quality control certificate with standard curve and evaluation table1
Storage
Store at 2-8°C.
Associated products
Bordetella pertussis Filamentous Hemagglutinin (FHA) Antigen (BA120VS3)
Bordetella pertussis Toxin Antigen (BA120VS4)
Bordetella pertussis whole cell Antigen (BA120VS8)
Bordetella pertussis Toxin Human IgA Assay Control (BC1201A)
Bordetella pertussis IgA Control Serum (BC120A)
Bordetella pertussis IgG Control Serum (BC120G)
Bordetella pertussis Toxin IgA ELISA Kit (ESR1201A)
Bordetella pertussis Toxin IgG ELISA Kit (ESR1201G)
Bordetella pertussis IgA ELISA Kit (ESR120A)
Bordetella pertussis IgG ELISA Kit (ESR120G)
Bordetella pertussis IgM ELISA Kit (ESR120M)
target relevance
Organism
Borrelia burgdorferi
Structure and strains
Borrelia burgdorferi is a bacterial species of the spirochete class in the genus Borrelia, and is one of the causative agents of Lyme disease in humans. Along with a few similar genospecies, some of which also cause Lyme disease, it makes up the species complex of Borrelia burgdorferi sensu lato. The complex currently comprises 20 accepted and 3 proposed genospecies.B. burgdorferi sensu stricto exists in North America and Eurasia and until 2016 was the only known cause of Lyme disease in North America. Borrelia species are Gram-negative.
Disease
Pathogens Borrelia burgdorferi is the infectious agent of Lyme-Borreliosis. B. burgdorferi sensu stricto, B. garinii, B. afzelii and B. spielmanii are the most important human pathogens of the genospecies Borrelia burgdorferi sensu lato. All four species are distributed throughout Europe in temperate climate zones. Reservoirs for the bacteria include a variety of mammals, particularly mice. The bacteria are transmitted to human hosts by infected ticks.

Lyme-Borreliosis is a multisystemic disease. Dermal manifestations with Erythema migrans (EM) as a characteristic symptom of early disease are displayed by 70 to 90 % of infected persons. In addition to non-specific symptoms, in particular neurological disorders, e. g. Morbus Bannwarth, may be observed between a few weeks and several months post infection as signs of a systemic disease with single or multiple organ involvement. Development of late-stage symptoms may occur up to several years after the tick bite and are characterized by dermatological diseases (Acrodermatitis chronica athrophicans), diseases of the joints (Lyme-Arthritis), and neurological diseases (chronical encephalomyelitis).
Detection and diagnosis
Due to the complexity of the clinical picture and the generally unspecific symptoms, serology is the appropriate method to ensure an optimal diagnosis. It is recommended to adopt a logical step-wise approach for serological diagnosis, initially using a sensitive screening assay with subsequent confirmation by another specific test.

Data

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




pmidtitleauthorscitation

Protocols

relevant to this product
ESR121G protocol

Documents

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