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Rubella Virus IgM ELISA Kit ESR129M

$325.00

Summary

  • Virion/Serion Diagnostic Kit for research use (RUO)
  • Rubella Virus IgM ELISA Kit
  • Suitable for IgM detection
  • Ready-to-use
  • 96 tests
Weight1 lbs
Dimensions9 × 5 × 2 in
target

Rubella Virus reactive IgM

species reactivity

Rubella Virus

applications

ELISA

assay type

Indirect & quantitative

available sizes

96 tests

Available product – Rubella Virus IgM ELISA Kit ESR129M

kit
Assay type
Indirect ELISA
Research area
Infectious Disease
Sample type
Serum, plasma, whole blood
Notes
Pretreatment of samples with RF-Absorbent (Z200) is recommended for use with IgM ELISA kits to eliminate presence of sample rheumatoid factors and possible false negative results.
Components
Break apart microtiter test strips each with antigen coated single wells8 x 12 (96 Total)
Standard serum (ready-to-use)2 x 2 mL
Negative control serum (ready-to-use)2 mL
Anti-human-IgM-conjugate (ready-to-use)13 mL
Washing solution concentrate (sufficient for 1000ml)33.3 mL
Dilution buffer2 x 50 mL
Stopping solution15 mL
Substrate (ready-to-use)13 mL
Quality control certificate with standard curve and evaluation table1
Storage
Store at 2-8°C.
Associated products
Rubella Virus Avidity Reagent (B129AVID)
Rubella Virus Grade 2 Antigen (BA129G2VS)
Rubella Spike Ectodomain (E1-E2) Antigen (BA129R01)
Rubella Virus IgG Control Serum (BC129G)
Rubella Virus IgM Control Serum (BC129M)
Rubella Virus IgG ELISA Kit (ESR129G)
Rubella Virus IgM ELISA Kit (ESR129M)
target relevance
Organism
Rubella Virus
Structure and strains
Rubella virus (RuV) is the pathogenic agent of the disease rubella, transmitted only between humans via the respiratory route, and is the main cause of congenital rubella syndrome when infection occurs during the first weeks of pregnancy.

Rubella virus, scientific name Rubivirus rubellae, is a member of the genus Rubivirus and belongs to the family of Matonaviridae, whose members commonly have a genome of single-stranded RNA of positive polarity which is enclosed by an icosahedral capsid.
Disease
Rubella Virus is a worldwide distributed human belonging to the Togavirus family of RNA viruses. It is transmitted by droplet infection.

Around 50 % of all Rubella Virus infections are asymptomatic and often remain undetected. Following an incubation period of 14 to 21 days a blotchy papular facial rash may appear and spread to the body and extremities. This usually fades after one to three days. Infected children display unspecific symptoms such as snuffles, fever, headache, joint pains and swelling of the lymph nodes in the neck and throat region. With increasing age rare complications may rise, which include arthritis, encephalitis and thrombocytopenia with a resulting tendency to bleeding. Rubella Virus infection during pregnancy may lead to severe damage in the fetus. Consequently, the
Detection and diagnosis
The detection of IgG antibodies directed against Rubella Virus by ELISA is valuable in determining the immune status. The detection of IgM antibodies is generally indicative of a primary infection, but can also be observed e. g. following reinfections. Due to the severe consequences for the fetus, pregnant women tested positive for IgM antibodies directed against Rubella Virus should be confirmed by additional testings, such as SERION avidity determination

Data

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




pmidtitleauthorscitation

Protocols

relevant to this product
ESR129M protocol

Documents

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