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Rubella Virus IgM ELISA kit-SERION classic ESR129M

$355.00

Summary

Virion/Serion Diagnostic Kit for research use (RUO)
Rubella Virus IgM ELISA Kit
Suitable for IgM detection
Ready-to-use
96 tests

SKU: ESR129M Category: Virion/Serion kits Tags: ELISA, IgM, Rubella Virus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Rubella Virus reactive IgM
species reactivity	Rubella Virus
applications	ELISA
assay type	Indirect & quantitative
available sizes	96 tests

Rubella Virus IgM ELISA Kit ESR129M

Assay type
Indirect ELISA

Research area
Infectious Disease

Sample type
Serum, plasma, whole blood

Notes
Pretreatment of samples with RF-Absorbent (Z200) is recommended for use with IgM ELISA kits to eliminate presence of sample rheumatoid factors and possible false negative results.

Components

Break apart microtiter test strips each with antigen coated single wells	8 x 12 (96 Total)
Standard serum (ready-to-use)	2 x 2 mL
Negative control serum (ready-to-use)	2 mL
Anti-human-IgM-conjugate (ready-to-use)	13 mL
Washing solution concentrate (sufficient for 1000ml)	33.3 mL
Dilution buffer	2 x 50 mL
Stopping solution	15 mL
Substrate (ready-to-use)	13 mL
Quality control certificate with standard curve and evaluation table	1

Storage
Store at 2-8°C.

Associated products
Rubella Virus Avidity Reagent (B129AVID)
Rubella Virus Grade 2 Antigen (BA129G2VS)
Rubella Spike Ectodomain (E1-E2) Antigen (BA129R01)
Rubella Virus IgG Control Serum (BC129G)
Rubella Virus IgM Control Serum (BC129M)
Rubella Virus IgG ELISA Kit (ESR129G)
Rubella Virus IgM ELISA Kit (ESR129M)

target relevance

human antibody anti-Rubella Virus

Rubella Virus

Description
Virus that causes rubella (German measles) and congenital rubella syndrome

Structure
Rubella virus is an enveloped, positive-sense, single-stranded RNA virus belonging to the genus Rubivirus within the family Matonaviridae. Humans are the only known natural host of the virus. The viral particle contains an icosahedral nucleocapsid surrounded by a lipid envelope bearing glycoproteins that mediate host cell attachment and entry. Rubella virus is transmitted primarily through respiratory droplets and direct contact with respiratory secretions. Following infection, the virus replicates in the upper respiratory tract and regional lymphoid tissues before disseminating throughout the body. Although rubella infection is generally mild in children and adults, infection during pregnancy can result in transplacental transmission and severe fetal abnormalities known as congenital rubella syndrome (CRS). Widespread vaccination programs have dramatically reduced the incidence of rubella in many regions of the world.

Diagnosis
The diagnosis of rubella virus infection is performed through serological and molecular methods. Detection of rubella-specific IgM antibodies by ELISA is commonly used to diagnose recent infection, while measurement of IgG antibodies can determine immune status or previous exposure. IgG avidity testing may help distinguish recent primary infection from past infection or vaccination. Molecular methods such as reverse transcription polymerase chain reaction (RT-PCR) can detect viral RNA in respiratory specimens, blood, amniotic fluid, or other clinical samples and are particularly valuable in cases of congenital infection. Laboratory confirmation is especially important in pregnant women because of the significant risk of fetal complications associated with maternal infection.

Symptoms
Rubella virus infection typically develops following an incubation period of approximately fourteen to twenty-one days. The disease is often mild and may be asymptomatic, particularly in children. Common symptoms include low-grade fever, malaise, headache, lymphadenopathy, and a characteristic fine pink maculopapular rash that usually begins on the face and spreads to the trunk and extremities. Swelling of the posterior auricular, occipital, and cervical lymph nodes is a characteristic clinical feature. Adults, particularly women, may experience arthralgia or arthritis. The most serious consequence of rubella infection occurs during pregnancy, especially during the first trimester, when fetal infection can result in congenital rubella syndrome characterized by hearing impairment, cataracts, congenital heart defects, developmental delay, growth restriction, and fetal loss.

Data

FAQ & Publications

Frequently Asked Questions

What is the primary application of the Rubella Virus IgM ELISA Kit ESR129M?

The Rubella Virus IgM ELISA Kit ESR129M is designed for the indirect and quantitative detection of Rubella Virus reactive IgM antibodies in serum, plasma, or whole blood samples, primarily for infectious disease research purposes.

How should samples be prepared to avoid false negative results when using this IgM ELISA kit?

It is recommended to pretreat samples with RF-Absorbent (Z200) to eliminate IgM rheumatoid factors, which can interfere with the assay and potentially cause false negative results.

What are the storage conditions for the Rubella Virus IgM ELISA Kit?

The kit components should be stored at 2-8°C to maintain stability and performance.

Is the Rubella Virus IgM ELISA Kit ESR129M suitable for detecting antibodies from species other than humans?

The kit is intended for detecting human IgM antibodies reactive to Rubella Virus; species reactivity is specific to Rubella Virus in human samples.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
ESR129M protocol

Documents

#
EP0120	Safety Data Sheet	QC certificate
EQ0236	Safety Data Sheet	QC certificate

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Rubella Virus IgM ELISA kit-SERION classic ESR129M

RF-Absorbent Z200 for use with IgM ELISA kits

Data

FAQ & Publications

Protocols

Documents

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Reviews

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