Rubella Virus Grade 2 Antigen BA129G2VS

$1,003.00

Summary

Virion/Serion Immunologics Antigen for research use (RUO)
Rubella Virus Grade 2 Antigen, recombinant
Suitable for detection of IgA, IgG & IgM antibodies in ELISA
Lot specific concentration, specified in mg/mL
1 mg

SKU: BA129G2VS Category: Infectious disease proteins Tags: antigen, Rubella Virus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Rubella Virus Grade 2
species reactivity	Rubella Virus
applications	ELISA
assay type	Indirect & quantitative
available size	1 mg

Rubella Virus Grade 2 Antigen BA129G2VS

kit
Research area Infectious Disease
Storage Store at -65°C or lower. Avoid repeated freeze-thaw cycles. Sonicate before use. 10 years from date of manufacture (under recommended storage conditions).
Form liquid
Associated products Rubella Virus Avidity Reagent (B129AVID) Rubella Virus Grade 2 Antigen (BA129G2VS) Rubella Spike Ectodomain (E1-E2) Antigen (BA129R01) Rubella Virus IgG Control Serum (BC129G) Rubella Virus IgM Control Serum (BC129M) Rubella Virus IgG ELISA Kit (ESR129G) Rubella Virus IgM ELISA Kit (ESR129M)

target relevance
Rubella Virus
Description Virus that causes rubella (German measles) and congenital rubella syndrome
Structure Rubella virus is an enveloped, positive-sense, single-stranded RNA virus belonging to the genus Rubivirus within the family Matonaviridae. Humans are the only known natural host of the virus. The viral particle contains an icosahedral nucleocapsid surrounded by a lipid envelope bearing glycoproteins that mediate host cell attachment and entry. Rubella virus is transmitted primarily through respiratory droplets and direct contact with respiratory secretions. Following infection, the virus replicates in the upper respiratory tract and regional lymphoid tissues before disseminating throughout the body. Although rubella infection is generally mild in children and adults, infection during pregnancy can result in transplacental transmission and severe fetal abnormalities known as congenital rubella syndrome (CRS). Widespread vaccination programs have dramatically reduced the incidence of rubella in many regions of the world.
Diagnosis The diagnosis of rubella virus infection is performed through serological and molecular methods. Detection of rubella-specific IgM antibodies by ELISA is commonly used to diagnose recent infection, while measurement of IgG antibodies can determine immune status or previous exposure. IgG avidity testing may help distinguish recent primary infection from past infection or vaccination. Molecular methods such as reverse transcription polymerase chain reaction (RT-PCR) can detect viral RNA in respiratory specimens, blood, amniotic fluid, or other clinical samples and are particularly valuable in cases of congenital infection. Laboratory confirmation is especially important in pregnant women because of the significant risk of fetal complications associated with maternal infection.
Symptoms Rubella virus infection typically develops following an incubation period of approximately fourteen to twenty-one days. The disease is often mild and may be asymptomatic, particularly in children. Common symptoms include low-grade fever, malaise, headache, lymphadenopathy, and a characteristic fine pink maculopapular rash that usually begins on the face and spreads to the trunk and extremities. Swelling of the posterior auricular, occipital, and cervical lymph nodes is a characteristic clinical feature. Adults, particularly women, may experience arthralgia or arthritis. The most serious consequence of rubella infection occurs during pregnancy, especially during the first trimester, when fetal infection can result in congenital rubella syndrome characterized by hearing impairment, cataracts, congenital heart defects, developmental delay, growth restriction, and fetal loss.

Data

FAQ & Publications

Frequently Asked Questions

What type of assays is the Rubella Virus Grade 2 Antigen BA129G2VS suitable for?

The Rubella Virus Grade 2 Antigen BA129G2VS is suitable for indirect and quantitative ELISA assays to detect IgA, IgG, and IgM antibodies.

How should the Rubella Virus Grade 2 Antigen be stored to maintain stability?

This antigen should be stored at -65°C or lower, avoiding repeated freeze-thaw cycles, and sonicated before use to ensure stability. Under these conditions, it can be stored for up to 10 years from the date of manufacture.

Which species does the Rubella Virus Grade 2 Antigen BA129G2VS react with?

The antigen specifically reacts with Rubella Virus, the target organism for this product.

What is the provided concentration and form of the Rubella Virus Grade 2 Antigen BA129G2VS?

The product is supplied as a liquid with lot-specific concentration specified in mg/mL, and the available size is 1 mg.

What is the relevance of detecting IgM and IgG antibodies against Rubella Virus using this antigen?

Detection of IgG antibodies indicates immune status, while IgM antibodies generally indicate primary infection or reinfection. For pregnant women testing positive for IgM, additional testing such as SERION avidity determination is recommended due to potential fetal risks.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.