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Rubella Virus IgG ELISA kit-SERION classic ESR129G

$355.00

Summary

Virion/Serion Diagnostic Kit for research use (RUO)
Rubella Virus IgG ELISA Kit
Suitable for IgG detection
Ready-to-use
96 tests

SKU: ESR129G Category: Virion/Serion kits Tags: ELISA, IgG, Rubella Virus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Rubella Virus reactive IgG
species reactivity	Rubella Virus
applications	ELISA
assay type	Indirect & quantitative
available sizes	96 tests

Rubella Virus IgG ELISA Kit ESR129G

Assay type
Indirect ELISA

Research area
Infectious Disease

Sample type
Serum, plasma, whole blood

Components

Break apart microtiter test strips each with antigen coated single wells	8 x 12 (96 Total)
Standard serum (ready-to-use)	2 x 2 mL
Negative control serum (ready-to-use)	2 mL
Anti-human-IgG-conjugate (ready-to-use)	13 mL
Washing solution concentrate (sufficient for 1000ml)	33.3 mL
Dilution buffer	2 x 50 mL
Stopping solution	15 mL
Substrate (ready-to-use)	13 mL
Quality control certificate with standard curve and evaluation table	1

Storage
Store at 2-8°C.

Associated products
Rubella Virus Avidity Reagent (B129AVID)
Rubella Virus Grade 2 Antigen (BA129G2VS)
Rubella Spike Ectodomain (E1-E2) Antigen (BA129R01)
Rubella Virus IgG Control Serum (BC129G)
Rubella Virus IgM Control Serum (BC129M)
Rubella Virus IgG ELISA Kit (ESR129G)
Rubella Virus IgM ELISA Kit (ESR129M)

target relevance

human antibody anti-Rubella Virus

Rubella Virus

Description
Virus that causes rubella (German measles) and congenital rubella syndrome

Structure
Rubella virus is an enveloped, positive-sense, single-stranded RNA virus belonging to the genus Rubivirus within the family Matonaviridae. Humans are the only known natural host of the virus. The viral particle contains an icosahedral nucleocapsid surrounded by a lipid envelope bearing glycoproteins that mediate host cell attachment and entry. Rubella virus is transmitted primarily through respiratory droplets and direct contact with respiratory secretions. Following infection, the virus replicates in the upper respiratory tract and regional lymphoid tissues before disseminating throughout the body. Although rubella infection is generally mild in children and adults, infection during pregnancy can result in transplacental transmission and severe fetal abnormalities known as congenital rubella syndrome (CRS). Widespread vaccination programs have dramatically reduced the incidence of rubella in many regions of the world.

Diagnosis
The diagnosis of rubella virus infection is performed through serological and molecular methods. Detection of rubella-specific IgM antibodies by ELISA is commonly used to diagnose recent infection, while measurement of IgG antibodies can determine immune status or previous exposure. IgG avidity testing may help distinguish recent primary infection from past infection or vaccination. Molecular methods such as reverse transcription polymerase chain reaction (RT-PCR) can detect viral RNA in respiratory specimens, blood, amniotic fluid, or other clinical samples and are particularly valuable in cases of congenital infection. Laboratory confirmation is especially important in pregnant women because of the significant risk of fetal complications associated with maternal infection.

Symptoms
Rubella virus infection typically develops following an incubation period of approximately fourteen to twenty-one days. The disease is often mild and may be asymptomatic, particularly in children. Common symptoms include low-grade fever, malaise, headache, lymphadenopathy, and a characteristic fine pink maculopapular rash that usually begins on the face and spreads to the trunk and extremities. Swelling of the posterior auricular, occipital, and cervical lymph nodes is a characteristic clinical feature. Adults, particularly women, may experience arthralgia or arthritis. The most serious consequence of rubella infection occurs during pregnancy, especially during the first trimester, when fetal infection can result in congenital rubella syndrome characterized by hearing impairment, cataracts, congenital heart defects, developmental delay, growth restriction, and fetal loss.

Data

FAQ & Publications

Frequently Asked Questions

What sample types are compatible with the Rubella Virus IgG ELISA Kit ESR129G?

The kit is compatible with serum, plasma, and whole blood samples for the detection of Rubella Virus reactive IgG antibodies.

How should the Rubella Virus IgG ELISA Kit ESR129G be stored to maintain stability?

The kit should be stored at 2-8°C to ensure reagent stability and optimal assay performance.

What is the assay format and detection principle used in the Rubella Virus IgG ELISA Kit ESR129G?

This kit utilizes an indirect and quantitative ELISA assay format to detect IgG antibodies against Rubella Virus.

Does the Rubella Virus IgG ELISA Kit ESR129G include all necessary reagents for performing 96 tests?

Yes, the kit contains all required components, including antigen-coated microtiter strips, controls, conjugate, substrate, buffers, washing solution, and stopping solution, sufficient for 96 tests.

Publications

pmid	title	authors	citation
41240950	Safety and non-inferiority of multidose and single-dose vial formulations of EuTCV Vi-CRM197 versus Typbar TCV in healthy participants in Kenya and Senegal: a multicentre, observer-blind, randomised, phase 3 study.	Birahim Pierre Ndiaye, Lucy Koech, Laina D Mercer, John J Aponte, Badara Cisse, Faith Riziki, Winnie Keter, Niles Eaton, Siry Diye, Djibril Wade, Ndeye Sakha Bob, Mike G Raine, Howard Her, Sookyung Kim, Rahsan Erdem, Chankyu Lee, Frederick J Cassels, Youngran Park, Moussa Dia, Yeong Ok Baik, Gamou Fall, Emily Locke, Patricia W Njuguna	Lancet Glob Health 13:e2122-e2132
41106800	Associations between serum metals and antibody levels against measles, rubella, and varicella vaccines in children with sex-specific nonlinear patterns.	Mei Liu, Pingting Zhu, Fenfang Deng, Boheng Liang, Yang Xu, Pengzhe Qin, Rongfei Peng, Lei Tan	Environ Pollut 386:127276
40912534	Spatial disparities in perfluoroalkyl and polyfluoroalkyl substances exposure and immunosuppressive effects on vaccine induced antibody levels in Guangzhou children.	Zhimei Mou, Pingting Zhu, Fenfang Deng, Yang Xu, Pengzhe Qin, Rongfei Peng, Juntao Li, Lei Tan	Environ Pollut 385:127066
39203968	A Serological Survey of Measles and Rubella Antibodies among Different Age Groups in Eastern China.	Rui Yan, Hanqing He, Xuan Deng, Yang Zhou, Xuewen Tang, Yao Zhu, Hui Liang, Yaping Chen, Mengya Yang, Yuxia Du, Can Chen, Jiaxin Chen, Shigui Yang, Ridphe Group	Vaccines (Basel) 12:N/A

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
ESR129G protocol

Documents

#
EP0167	Safety Data Sheet	QC certificate
EQ0165	Safety Data Sheet	QC certificate

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Rubella Virus IgG ELISA kit-SERION classic ESR129G

Data

FAQ & Publications

Protocols

Documents

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Reviews

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