Rubella Virus IgM Control Serum BC129M

$94.00

Summary

Virion/Serion Diagnostic Kit Control for research use (RUO)
Rubella Virus IgM Control Serum
Applications: ELISA
IgM control serum
Ready-to-use; pre-diluted for SERION ELISA classic and SERION ELISA antigen assays
3 mL

SKU: BC129M Categories: control serum, Virion/Serion kits Tags: ELISA control serum, IgM, Rubella Virus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Rubella Virus reactive IgM
species reactivity	Rubella Virus
applications	ELISA
assay type	Indirect & quantitative
available size	3 mL

Rubella Virus IgM Control Serum BC129M

kit
Research area Infectious Disease
Storage Store at 2-8°C.
Associated products Rubella Virus Avidity Reagent (B129AVID) Rubella Virus Grade 2 Antigen (BA129G2VS) Rubella Spike Ectodomain (E1-E2) Antigen (BA129R01) Rubella Virus IgG Control Serum (BC129G) Rubella Virus IgM Control Serum (BC129M) Rubella Virus IgG ELISA Kit (ESR129G) Rubella Virus IgM ELISA Kit (ESR129M)

target relevance

human antibody anti-Rubella Virus

Rubella Virus

Description
Virus that causes rubella (German measles) and congenital rubella syndrome

Structure
Rubella virus is an enveloped, positive-sense, single-stranded RNA virus belonging to the genus Rubivirus within the family Matonaviridae. Humans are the only known natural host of the virus. The viral particle contains an icosahedral nucleocapsid surrounded by a lipid envelope bearing glycoproteins that mediate host cell attachment and entry. Rubella virus is transmitted primarily through respiratory droplets and direct contact with respiratory secretions. Following infection, the virus replicates in the upper respiratory tract and regional lymphoid tissues before disseminating throughout the body. Although rubella infection is generally mild in children and adults, infection during pregnancy can result in transplacental transmission and severe fetal abnormalities known as congenital rubella syndrome (CRS). Widespread vaccination programs have dramatically reduced the incidence of rubella in many regions of the world.

Diagnosis
The diagnosis of rubella virus infection is performed through serological and molecular methods. Detection of rubella-specific IgM antibodies by ELISA is commonly used to diagnose recent infection, while measurement of IgG antibodies can determine immune status or previous exposure. IgG avidity testing may help distinguish recent primary infection from past infection or vaccination. Molecular methods such as reverse transcription polymerase chain reaction (RT-PCR) can detect viral RNA in respiratory specimens, blood, amniotic fluid, or other clinical samples and are particularly valuable in cases of congenital infection. Laboratory confirmation is especially important in pregnant women because of the significant risk of fetal complications associated with maternal infection.

Symptoms
Rubella virus infection typically develops following an incubation period of approximately fourteen to twenty-one days. The disease is often mild and may be asymptomatic, particularly in children. Common symptoms include low-grade fever, malaise, headache, lymphadenopathy, and a characteristic fine pink maculopapular rash that usually begins on the face and spreads to the trunk and extremities. Swelling of the posterior auricular, occipital, and cervical lymph nodes is a characteristic clinical feature. Adults, particularly women, may experience arthralgia or arthritis. The most serious consequence of rubella infection occurs during pregnancy, especially during the first trimester, when fetal infection can result in congenital rubella syndrome characterized by hearing impairment, cataracts, congenital heart defects, developmental delay, growth restriction, and fetal loss.

Data

FAQ & Publications

Frequently Asked Questions

What is the intended application for the Rubella Virus IgM Control Serum BC129M?

The Rubella Virus IgM Control Serum BC129M is designed for use as a control serum in ELISA assays, specifically for detecting Rubella Virus reactive IgM antibodies.

How should the Rubella Virus IgM Control Serum BC129M be stored to maintain its stability?

This control serum should be stored at temperatures between 2-8°C to ensure proper preservation and stability.

Is the Rubella Virus IgM Control Serum BC129M compatible with specific ELISA kits?

Yes, the serum is ready-to-use and pre-diluted for compatibility with SERION ELISA classic and SERION ELISA antigen assays.

Which species does the Rubella Virus IgM Control Serum BC129M target?

The control serum targets IgM antibodies reactive to the Rubella Virus, which infects humans exclusively.

What volume does the Rubella Virus IgM Control Serum BC129M come in?

This product is supplied as a 3 mL ready-to-use serum.

Publications

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We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
BC129M protocol

Documents

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Rubella Virus IgM Control Serum BC129M

Data

FAQ & Publications

Protocols

Documents

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Reviews

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