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Varicella-Zoster Virus IgM ELISA kit-SERION classic ESR104M

$364.00

Summary

Virion/Serion Diagnostic Kit for research use (RUO)
Varicella-Zoster Virus IgM ELISA Kit
Suitable for IgM detection
Ready-to-use
96 tests

SKU: ESR104M Category: Virion/Serion kits Tags: ELISA, IgM, Varicella-Zoster Virus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Varicella-Zoster Virus reactive IgM
species reactivity	Varicella-Zoster Virus
applications	ELISA
assay type	Indirect & quantitative
available sizes	96 tests

Varicella-Zoster Virus IgM ELISA Kit ESR104M

Assay type
Indirect ELISA

Research area
Infectious Disease

Sample type
Serum, plasma, whole blood

Notes
Pretreatment of samples with RF-Absorbent (Z200) is recommended for use with IgM ELISA kits to eliminate presence of sample rheumatoid factors and possible false negative results.

Components

Break apart microtiter test strips each with antigen coated single wells	8 x 12 (96 Total)
Standard serum (ready-to-use)	2 x 2 mL
Negative control serum (ready-to-use)	2 mL
Anti-human-IgM-conjugate (ready-to-use)	13 mL
Washing solution concentrate (sufficient for 1000ml)	33.3 mL
Dilution buffer	2 x 50 mL
Stopping solution	15 mL
Substrate (ready-to-use)	13 mL
Quality control certificate with standard curve and evaluation table	1

Storage
Store at 2-8°C.

Associated products
Varicella Zoster Virus (VZV) Envelope Glycoprotein E Control Antigen (BA104R02)
Varicella-Zoster Virus Antigen (BA104VS)
Varicella-Zoster Virus Glycoprotein Antigen (BA104VSG)
Varicella-Zoster Virus IgA Control Serum (BC104A)
Varicella-Zoster Virus IgG Control Serum (BC104G)
Varicella-Zoster Virus IgM Control Serum (BC104M)
Varicella-Zoster Virus IgA ELISA Kit (ESR104A)
Varicella-Zoster Virus IgG ELISA Kit (ESR104G)
Varicella-Zoster Virus IgM ELISA Kit (ESR104M)

target relevance

human antibody anti-Varicella-ZosterVirus

Varicella-ZosterVirus

Description
Virus that causes chickenpox (varicella) and shingles (herpes zoster)

Structure
Varicella-zoster virus (VZV), also known as Human herpesvirus 3 (HHV-3), is an enveloped, double-stranded DNA virus belonging to the genus Varicellovirus within the family Herpesviridae. The viral genome is enclosed within an icosahedral capsid surrounded by a protein tegument and a lipid envelope containing multiple glycoproteins that mediate host cell attachment and entry. Humans are the only known natural reservoir of the virus. Primary infection results in varicella (chickenpox), after which the virus establishes lifelong latency within sensory nerve ganglia. Reactivation of latent virus later in life results in herpes zoster (shingles). Varicella-zoster virus is highly contagious and spreads primarily through respiratory droplets, aerosolized virus from skin lesions, and direct contact with vesicular fluid.

Diagnosis
The diagnosis of varicella-zoster virus infection is performed through clinical evaluation, molecular testing, and serological methods. Polymerase chain reaction (PCR) is the preferred laboratory method due to its high sensitivity and specificity and can detect VZV DNA in vesicular fluid, lesion swabs, cerebrospinal fluid, blood, and tissue specimens. Direct fluorescent antibody testing and viral culture may also be used but are less sensitive than PCR. Serological assays, including ELISA-based tests, can detect VZV-specific IgM and IgG antibodies and are useful for determining immune status, previous exposure, or vaccine response. Laboratory confirmation is particularly important in atypical cases, immunocompromised patients, and individuals with suspected neurological complications.

Symptoms
Primary infection with varicella-zoster virus typically develops after an incubation period of approximately ten to twenty-one days and presents as chickenpox, characterized by fever, malaise, headache, and a generalized pruritic vesicular rash that progresses through macular, papular, vesicular, and crusting stages. Following recovery, the virus remains latent in sensory ganglia and may reactivate years or decades later as shingles. Herpes zoster is characterized by painful, unilateral vesicular eruptions distributed along affected dermatomes and is often preceded by burning, tingling, or localized pain. Complications of VZV infection include secondary bacterial skin infections, pneumonia, encephalitis, meningitis, cerebellitis, vision-threatening ophthalmic zoster, and postherpetic neuralgia, a chronic pain syndrome that may persist long after skin lesions have resolved. Severe disease is more common in elderly individuals, pregnant women, newborns, and immunocompromised patients.

Data

FAQ & Publications

Frequently Asked Questions

What sample types are compatible with the Varicella-Zoster Virus IgM ELISA Kit ESR104M?

The Varicella-Zoster Virus IgM ELISA Kit ESR104M is compatible with serum, plasma, and whole blood samples for the detection of Varicella-Zoster Virus reactive IgM antibodies.

Why is pretreatment with RF-Absorbent (Z200) recommended when using this IgM ELISA kit?

Pretreatment of samples with RF-Absorbent (Z200) is recommended to remove IgM rheumatoid factors from serum and plasma samples, which can interfere with the assay and potentially cause false negative results. This improves signal specificity in the detection of pathogen-specific IgM antibodies.

How should the Varicella-Zoster Virus IgM ELISA Kit ESR104M be stored to maintain stability?

The kit components should be stored at 2-8°C to ensure stability and optimal performance throughout the shelf life of the Varicella-Zoster Virus IgM ELISA Kit ESR104M.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
ESR104M protocol

Documents

#
EP0006	Safety Data Sheet	QC certificate
EP0134	Safety Data Sheet	QC certificate
EQ0112	Safety Data Sheet	QC certificate
EQ0194	Safety Data Sheet	QC certificate

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Varicella-Zoster Virus IgM ELISA kit-SERION classic ESR104M

RF-Absorbent Z200 for use with IgM ELISA kits

Data

FAQ & Publications

Protocols

Documents

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Reviews

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