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Varicella-Zoster Virus IgG ELISA kit-SERION classic ESR104G

$364.00

Summary

Virion/Serion Diagnostic Kit for research use (RUO)
Varicella-Zoster Virus IgG ELISA Kit
Suitable for IgG detection
Ready-to-use
96 tests

SKU: ESR104G Category: Virion/Serion kits Tags: ELISA, IgG, Varicella-Zoster Virus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Varicella-Zoster Virus reactive IgG
species reactivity	Varicella-Zoster Virus
applications	ELISA
assay type	Indirect & quantitative
available sizes	96 tests

Varicella-Zoster Virus IgG ELISA Kit ESR104G

Assay type
Indirect ELISA

Research area
Infectious Disease

Sample type
Serum, plasma, whole blood

Components

Break apart microtiter test strips each with antigen coated single wells	8 x 12 (96 Total)
Standard serum (ready-to-use)	2 x 2 mL
Negative control serum (ready-to-use)	2 mL
Anti-human-IgG-conjugate (ready-to-use)	13 mL
Washing solution concentrate (sufficient for 1000ml)	33.3 mL
Dilution buffer	2 x 50 mL
Stopping solution	15 mL
Substrate (ready-to-use)	13 mL
Quality control certificate with standard curve and evaluation table	1

Storage
Store at 2-8°C.

Associated products
Varicella Zoster Virus (VZV) Envelope Glycoprotein E Control Antigen (BA104R02)
Varicella-Zoster Virus Antigen (BA104VS)
Varicella-Zoster Virus Glycoprotein Antigen (BA104VSG)
Varicella-Zoster Virus IgA Control Serum (BC104A)
Varicella-Zoster Virus IgG Control Serum (BC104G)
Varicella-Zoster Virus IgM Control Serum (BC104M)
Varicella-Zoster Virus IgA ELISA Kit (ESR104A)
Varicella-Zoster Virus IgG ELISA Kit (ESR104G)
Varicella-Zoster Virus IgM ELISA Kit (ESR104M)

target relevance

human antibody anti-Varicella-ZosterVirus

Varicella-ZosterVirus

Description
Virus that causes chickenpox (varicella) and shingles (herpes zoster)

Structure
Varicella-zoster virus (VZV), also known as Human herpesvirus 3 (HHV-3), is an enveloped, double-stranded DNA virus belonging to the genus Varicellovirus within the family Herpesviridae. The viral genome is enclosed within an icosahedral capsid surrounded by a protein tegument and a lipid envelope containing multiple glycoproteins that mediate host cell attachment and entry. Humans are the only known natural reservoir of the virus. Primary infection results in varicella (chickenpox), after which the virus establishes lifelong latency within sensory nerve ganglia. Reactivation of latent virus later in life results in herpes zoster (shingles). Varicella-zoster virus is highly contagious and spreads primarily through respiratory droplets, aerosolized virus from skin lesions, and direct contact with vesicular fluid.

Diagnosis
The diagnosis of varicella-zoster virus infection is performed through clinical evaluation, molecular testing, and serological methods. Polymerase chain reaction (PCR) is the preferred laboratory method due to its high sensitivity and specificity and can detect VZV DNA in vesicular fluid, lesion swabs, cerebrospinal fluid, blood, and tissue specimens. Direct fluorescent antibody testing and viral culture may also be used but are less sensitive than PCR. Serological assays, including ELISA-based tests, can detect VZV-specific IgM and IgG antibodies and are useful for determining immune status, previous exposure, or vaccine response. Laboratory confirmation is particularly important in atypical cases, immunocompromised patients, and individuals with suspected neurological complications.

Symptoms
Primary infection with varicella-zoster virus typically develops after an incubation period of approximately ten to twenty-one days and presents as chickenpox, characterized by fever, malaise, headache, and a generalized pruritic vesicular rash that progresses through macular, papular, vesicular, and crusting stages. Following recovery, the virus remains latent in sensory ganglia and may reactivate years or decades later as shingles. Herpes zoster is characterized by painful, unilateral vesicular eruptions distributed along affected dermatomes and is often preceded by burning, tingling, or localized pain. Complications of VZV infection include secondary bacterial skin infections, pneumonia, encephalitis, meningitis, cerebellitis, vision-threatening ophthalmic zoster, and postherpetic neuralgia, a chronic pain syndrome that may persist long after skin lesions have resolved. Severe disease is more common in elderly individuals, pregnant women, newborns, and immunocompromised patients.

Data

FAQ & Publications

Frequently Asked Questions

What sample types are compatible with the Varicella-Zoster Virus IgG ELISA Kit ESR104G?

The Varicella-Zoster Virus IgG ELISA Kit ESR104G is compatible with serum, plasma, and whole blood samples for IgG antibody detection.

How should the Varicella-Zoster Virus IgG ELISA Kit ESR104G be stored to maintain stability?

The kit should be stored at 2-8°C to ensure reagent stability and optimal assay performance.

What components are included in the Varicella-Zoster Virus IgG ELISA Kit ESR104G for conducting 96 tests?

The kit includes 8 x 12 break-apart microtiter strips coated with antigen, standard serum, negative control serum, anti-human-IgG-conjugate, washing solution concentrate, dilution buffer, stopping solution, substrate, and a quality control certificate with standard curve and evaluation table.

Publications

pmid	title	authors	citation
41882028	Evaluating varicella-zoster virus vaccine immunogenicity through Fc-mediated antibody functions: the roles of ADCP and ADCC.	Sivilay Xayaheuang, Ji-Young Hwang, Yunhwa Kim, Kyung-Min Lee, Seok-Tae Choi, Eun-Jeong Jang, Ji-Soo Lim, Ji Young Bang, Han Sol Lee, Ok Sarah Shin, Ji Yun Noh, So-Hee Hong, Hosun Park	NPJ Vaccines N/A:N/A
41106800	Associations between serum metals and antibody levels against measles, rubella, and varicella vaccines in children with sex-specific nonlinear patterns.	Mei Liu, Pingting Zhu, Fenfang Deng, Boheng Liang, Yang Xu, Pengzhe Qin, Rongfei Peng, Lei Tan	Environ Pollut 386:127276
40912534	Spatial disparities in perfluoroalkyl and polyfluoroalkyl substances exposure and immunosuppressive effects on vaccine induced antibody levels in Guangzhou children.	Zhimei Mou, Pingting Zhu, Fenfang Deng, Yang Xu, Pengzhe Qin, Rongfei Peng, Juntao Li, Lei Tan	Environ Pollut 385:127066
38921797	Cytomegalovirus, Epstein-Barr Virus, Herpes Simplex Virus, and Varicella Zoster Virus Infection Dynamics in People with Multiple Sclerosis from Northern Italy.	Peter A Maple, Radu Tanasescu, Cris S Constantinescu, Paola Valentino, Marco Capobianco, Silvia D'Orso, Giovanna Borsellino, Luca Battistini, Giovanni Ristori, Rosella Mechelli, Marco Salvetti, Bruno Gran	Pathogens 13:N/A
38543925	Study on Varicella-Zoster Virus Antibody Levels among Children Aged 1-7 Years in Changzhou, China.	Dan Wu, Changlei Han, Suting Xiong, Peipei Zhang, Han Gao, Junhong Li, Fengming Wang, Qinwen Xu, Xin Dong	Vaccines (Basel) 12:N/A

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
ESR104G protocol

Documents

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EP0064	Safety Data Sheet	QC certificate
EQ0003	Safety Data Sheet	QC certificate
EQ0138	Safety Data Sheet	QC certificate

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Varicella-Zoster Virus IgG ELISA kit-SERION classic ESR104G

Data

FAQ & Publications

Protocols

Documents

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Reviews

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