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Toxoplasma gondii IgM ELISA kit-SERION classic ESR110M

$355.00

Summary

Virion/Serion Diagnostic Kit for research use (RUO)
Toxoplasma gondii IgM ELISA Kit
Suitable for IgM detection
Ready-to-use
96 tests

SKU: ESR110M Category: Virion/Serion kits Tags: ELISA, IgM, Toxoplasma gondii

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Toxoplasma gondii reactive IgM
species reactivity	Toxoplasma gondii
applications	ELISA
assay type	Indirect & quantitative
available sizes	96 tests

Toxoplasma gondii IgM ELISA Kit ESR110M

Assay type
Indirect ELISA

Research area
Infectious Disease

Sample type
Serum, plasma, whole blood

Notes
Pretreatment of samples with RF-Absorbent (Z200) is recommended for use with IgM ELISA kits to eliminate presence of sample rheumatoid factors and possible false negative results.

Components

Break apart microtiter test strips each with antigen coated single wells	8 x 12 (96 Total)
Standard serum (ready-to-use)	2 x 2 mL
Negative control serum (ready-to-use)	2 mL
Anti-human-IgM-conjugate (ready-to-use)	13 mL
Washing solution concentrate (sufficient for 1000ml)	33.3 mL
Dilution buffer	2 x 50 mL
Stopping solution	15 mL
Substrate (ready-to-use)	13 mL
Quality control certificate with standard curve and evaluation table	1

Storage
Store at 2-8°C.

Associated products
Toxoplasma gondii Avidity Reagent (B110AVID)
Toxoplasma gondii Antigen (BA110VS)
Toxoplasma gondii IgG Control Serum (BC110G)
Toxoplasma gondii IgM Control Serum (BC110M)
Toxoplasma gondii IgG ELISA Kit (ESR110G)
Toxoplasma gondii IgM ELISA Kit (ESR110M)

target relevance

human antibody anti-Toxoplasma gondii

Toxoplasma gondii

Description
Protozoan parasite that causes toxoplasmosis

Structure
Toxoplasma gondii is an obligate intracellular protozoan parasite belonging to the phylum Apicomplexa. The parasite has a complex life cycle involving both sexual and asexual stages. Members of the cat family (Felidae) serve as the definitive hosts in which sexual reproduction occurs, while a wide range of warm-blooded animals, including humans, act as intermediate hosts. T. gondii exists in several developmental forms, including rapidly dividing tachyzoites, slowly replicating tissue cysts containing bradyzoites, and environmentally resistant oocysts shed in feline feces. The parasite is distributed worldwide and is one of the most common parasitic infections of humans. Following infection, T. gondii can establish lifelong latent infection within muscle and neural tissues through the formation of tissue cysts.

Diagnosis
The diagnosis of Toxoplasma gondii infection is performed through serological, molecular, histological, and microbiological methods. Serological testing is the most commonly used diagnostic approach and includes detection of Toxoplasma-specific IgM and IgG antibodies using ELISA and other immunoassays. Measurement of antibody avidity may help distinguish recent from past infection. Molecular techniques such as polymerase chain reaction (PCR) are widely used for detecting parasite DNA in blood, cerebrospinal fluid, amniotic fluid, and tissue specimens, particularly in congenital infections and immunocompromised patients. Histopathological examination and direct visualization of parasites may also aid diagnosis in selected cases. Early diagnosis is especially important during pregnancy because of the risk of congenital transmission.

Symptoms
Most immunocompetent individuals infected with Toxoplasma gondii remain asymptomatic or develop mild flu-like symptoms, including fever, fatigue, headache, muscle aches, and lymphadenopathy. Following primary infection, the parasite establishes latent infection that may persist for life. In immunocompromised individuals, including patients with advanced HIV infection, organ transplant recipients, and individuals receiving immunosuppressive therapy, reactivation of latent infection can cause severe disease, particularly toxoplasmic encephalitis characterized by headache, confusion, seizures, focal neurological deficits, and altered mental status. Congenital toxoplasmosis can occur when infection is acquired during pregnancy and may result in miscarriage, stillbirth, hydrocephalus, intracranial calcifications, chorioretinitis, vision impairment, developmental delay, and other severe neurological complications.

Data

FAQ & Publications

Frequently Asked Questions

What sample types are compatible with the Toxoplasma gondii IgM ELISA Kit ESR110M?

The Toxoplasma gondii IgM ELISA Kit ESR110M is compatible with serum, plasma, and whole blood samples for the detection of IgM antibodies.

How should the Toxoplasma gondii IgM ELISA Kit ESR110M be stored to maintain its stability?

The kit should be stored at 2-8°C to preserve its components and ensure reliable assay performance.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
ESR110M protocol

Documents

#
ER0115	Safety Data Sheet	QC certificate

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Toxoplasma gondii IgM ELISA kit-SERION classic ESR110M

RF-Absorbent Z200 for use with IgM ELISA kits

Data

FAQ & Publications

Protocols

Documents

Related Technical Resources & Posts

Reviews

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