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Toxoplasma gondii IgG Control Serum BC110G

$94.00

Summary

  • Virion/Serion Diagnostic Kit Control for research use (RUO)
  • Toxoplasma gondii IgG Control Serum
  • Applications: ELISA
  • IgG control serum
  • Ready-to-use; pre-diluted for SERION ELISA classic and SERION ELISA antigen assays
  • 3 mL
Weight1 lbs
Dimensions9 × 5 × 2 in
target

Toxoplasma gondii reactive IgG

species reactivity

Toxoplasma gondii

applications

ELISA

assay type

Indirect & quantitative

available size

3 mL

Available product – Toxoplasma gondii IgG Control Serum BC110G

kit
Research area
Infectious Disease
Storage
Store at 2-8°C.
Associated products
Toxoplasma gondii Avidity Reagent (B110AVID)
Toxoplasma gondii Antigen (BA110VS)
Toxoplasma gondii IgG Control Serum (BC110G)
Toxoplasma gondii IgM Control Serum (BC110M)
Toxoplasma gondii IgG ELISA Kit (ESR110G)
Toxoplasma gondii IgM ELISA Kit (ESR110M)
target relevance
Organism
Toxoplasma gondii
Structure and strains
Toxoplasma gondii is a parasitic protozoan (specifically an apicomplexan) that causes toxoplasmosis. Found worldwide, T. gondii is capable of infecting virtually all warm-blooded animals,: 1 but felids are the only known definitive hosts in which the parasite may undergo sexual reproduction.
Disease
Toxoplasma gondii is an eucaryotic protozoa of the sporozoa group. The obligatory intracellular parasite is distributed worldwide.

Following oral uptake of the parasite, e. g. with contaminated food, the organism penetrates the gut and enters the reticuloendothelial system. Due to the following hematogenous dissemination, Toxoplasma gondii is able to infect many different organs and tissues. Approximately 50% of infections with Toxoplasma gondii proceed subclinically. The remainder demonstrate only unspecific symptoms such as low fever, exhaustion, headache as well as muscle and joint pain after an incubation period of one to three weeks. A minority of patients suffer from high fever up to 39°C and swelling of lymph nodes. In 1% of infected children and young adults complications such as myocarditis, meningitis or pneumonia are reported. After recovery, Toxoplasma gondii persists in infected tissues by forming cysts.
Detection and diagnosis
The diagnosis of toxoplasmosis is based on clinical findings and serological investigations. ELISA tests are recommended for the demonstration of IgG and IgM antibodies. Screening for Toxoplasma infections during pregnancy is of significant importance in prenatal care. The transmission of Toxoplasma gondii via the transplacental route has been observed in all stages of pregnancy, although the risk of a prenatal transmission as well as the outcome of infection depends on the stage of pregnancy. The risk of an infection of the unborn child via transplacental transmission is limited to seronegative women who acquire a primary infection during pregnancy. IgM antibodies directed against Toxoplasma gondii can persist for months after infection. Therefore, the determination of the IgG antibody avidity allows for differentiation of primary from past infections.

Data

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




pmidtitleauthorscitation

Protocols

relevant to this product
BC110G protocol

Documents

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