Toxoplasma gondii IgM Control Serum BC110M

$94.00

Summary

Virion/Serion Diagnostic Kit Control for research use (RUO)
Toxoplasma gondii IgM Control Serum
Applications: ELISA
IgM control serum
Ready-to-use; pre-diluted for SERION ELISA classic and SERION ELISA antigen assays
3 mL

SKU: BC110M Categories: control serum, Virion/Serion kits Tags: ELISA control serum, IgM, Toxoplasma gondii

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Toxoplasma gondii reactive IgM
species reactivity	Toxoplasma gondii
applications	ELISA
assay type	Indirect & quantitative
available size	3 mL

Toxoplasma gondii IgM Control Serum BC110M

kit
Research area Infectious Disease
Storage Store at 2-8°C.
Associated products Toxoplasma gondii Avidity Reagent (B110AVID) Toxoplasma gondii Antigen (BA110VS) Toxoplasma gondii IgG Control Serum (BC110G) Toxoplasma gondii IgM Control Serum (BC110M) Toxoplasma gondii IgG ELISA Kit (ESR110G) Toxoplasma gondii IgM ELISA Kit (ESR110M)

target relevance

human antibody anti-Toxoplasma gondii

Toxoplasma gondii

Description
Protozoan parasite that causes toxoplasmosis

Structure
Toxoplasma gondii is an obligate intracellular protozoan parasite belonging to the phylum Apicomplexa. The parasite has a complex life cycle involving both sexual and asexual stages. Members of the cat family (Felidae) serve as the definitive hosts in which sexual reproduction occurs, while a wide range of warm-blooded animals, including humans, act as intermediate hosts. T. gondii exists in several developmental forms, including rapidly dividing tachyzoites, slowly replicating tissue cysts containing bradyzoites, and environmentally resistant oocysts shed in feline feces. The parasite is distributed worldwide and is one of the most common parasitic infections of humans. Following infection, T. gondii can establish lifelong latent infection within muscle and neural tissues through the formation of tissue cysts.

Diagnosis
The diagnosis of Toxoplasma gondii infection is performed through serological, molecular, histological, and microbiological methods. Serological testing is the most commonly used diagnostic approach and includes detection of Toxoplasma-specific IgM and IgG antibodies using ELISA and other immunoassays. Measurement of antibody avidity may help distinguish recent from past infection. Molecular techniques such as polymerase chain reaction (PCR) are widely used for detecting parasite DNA in blood, cerebrospinal fluid, amniotic fluid, and tissue specimens, particularly in congenital infections and immunocompromised patients. Histopathological examination and direct visualization of parasites may also aid diagnosis in selected cases. Early diagnosis is especially important during pregnancy because of the risk of congenital transmission.

Symptoms
Most immunocompetent individuals infected with Toxoplasma gondii remain asymptomatic or develop mild flu-like symptoms, including fever, fatigue, headache, muscle aches, and lymphadenopathy. Following primary infection, the parasite establishes latent infection that may persist for life. In immunocompromised individuals, including patients with advanced HIV infection, organ transplant recipients, and individuals receiving immunosuppressive therapy, reactivation of latent infection can cause severe disease, particularly toxoplasmic encephalitis characterized by headache, confusion, seizures, focal neurological deficits, and altered mental status. Congenital toxoplasmosis can occur when infection is acquired during pregnancy and may result in miscarriage, stillbirth, hydrocephalus, intracranial calcifications, chorioretinitis, vision impairment, developmental delay, and other severe neurological complications.

Data

FAQ & Publications

Frequently Asked Questions

What is the specific application of the Toxoplasma gondii IgM Control Serum BC110M?

The Toxoplasma gondii IgM Control Serum BC110M is designed for use as a control in ELISA applications, specifically for the detection of IgM antibodies against Toxoplasma gondii in indirect and quantitative assays.

How should the Toxoplasma gondii IgM Control Serum BC110M be stored to maintain its stability?

This control serum should be stored refrigerated at temperatures between 2-8°C to ensure optimal stability and performance.

Is the Toxoplasma gondii IgM Control Serum BC110M compatible with specific diagnostic kits?

Yes, the serum is ready-to-use and pre-diluted for compatibility with SERION ELISA classic and SERION ELISA antigen assays, facilitating straightforward integration into these diagnostic workflows.

Publications

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We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
BC110M protocol

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Toxoplasma gondii IgM Control Serum BC110M

Data

FAQ & Publications

Protocols

Documents

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