Immunohistochemistry (IHC) : Human Hodgkin lymphoma stained with anti-CD30 antibody using peroxidase-conjugate and DAB chromogen. Note the membranous staining of Hodgkin’s cells.

rabbit anti-CD30 monoclonal antibody (ZR248) 6084

$160.00 – $528.00

Antibody summary

Rabbit monoclonal to CD30
Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Reacts with: Human
Isotype:IgG
Control: Hodgkin lymphoma or anaplastic large cell lymphoma
Visualization: Cell membrane and cytoplasmic
0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted

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SKU: 6084parent Category: antibody Tags: anatomy, CD30, Hematopathology

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgG
clonality	monoclonal
concentration	concentrate, predilute
applications	IHC
reactivity	human
available size	0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

rabbit anti-CD30 monoclonal antibody ZR248 6084

antibody
Database link: human P28908
Tested applications IHC
Recommended dilutions Concentrated 1:100-200
Application Notes Positive control: Hodgkin lymphoma or anaplastic large cell lymphoma
Immunogen Recombinant human full-length TNFRSF8 protein (CD30)
Size and concentration 7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form liquid
Storage Instructions 2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity affinity purified
Clonality monoclonal
Isotype IgG
Compatible secondaries goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863 goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720
Isotype control Rabbit polyclonal - Isotype Control

target relevance
Protein names Tumor necrosis factor receptor superfamily member 8 (CD30L receptor) (Ki-1 antigen) (Lymphocyte activation antigen CD30) (CD antigen CD30)
Gene names TNFRSF8,TNFRSF8 CD30 D1S166E
Protein family TNFR8 family
Mass 63747Da
Function FUNCTION: Receptor for TNFSF8/CD30L (PubMed:8391931). May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (PubMed:8999898). {ECO:0000269\|PubMed:8391931, ECO:0000269\|PubMed:8999898}.
Subellular location SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane {ECO:0000269\|PubMed:8391931, ECO:0000305\|PubMed:8999898}; Single-pass type I membrane protein {ECO:0000255}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000269\|PubMed:8839832}.
Tissues TISSUE SPECIFICITY: [Isoform 2]: Detected in alveolar macrophages (at protein level). {ECO:0000269\|PubMed:8839832}.
Structure SUBUNIT: Interacts with TRAF1, TRAF2, TRAF3 and TRAF5. {ECO:0000269\|PubMed:10518213, ECO:0000269\|PubMed:8627180, ECO:0000269\|PubMed:8999898, ECO:0000269\|PubMed:9168896, ECO:0000269\|PubMed:9511754}.
Post-translational modification PTM: Phosphorylated on serine and tyrosine residues (Probable). Isoform 2 is constitutively phosphorylated (PubMed:8839832). {ECO:0000269\|PubMed:8839832, ECO:0000305}.
Target Relevance information above includes information from UniProt accession: P28908
The UniProt Consortium

Data

Human Hodgkin lymphoma stained with anti-CD30 antibody using peroxidase-conjugate and DAB chromogen. Note the membranous staining of Hodgkin's cells.

Publications

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We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.