Immunohistochemistry (IHC) : Human Hodgkin lymphoma stained with anti-CD30 antibody using peroxidase-conjugate and DAB chromogen. Note the membranous staining of Hodgkin’s cells.

mouse anti-CD30 monoclonal antibody (Ber-H2) 6083

$160.00 – $528.00

Antibody summary

Mouse monoclonal to CD30
Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Reacts with: Human
Isotype:IgG1
Control: Hodgkin lymphoma or anaplastic large cell lymphoma
Visualization: Cell membrane and cytoplasmic
0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted

SKU: 6083parent Category: antibody Tags: anatomy, CD30, Hematopathology

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgG1
clonality	monoclonal
concentration	concentrate, predilute
applications	IHC
reactivity	human
available size	0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

mouse anti-CD30 monoclonal antibody Ber-H2 6083

antibody
Database link: human P28908
Tested applications IHC
Recommended dilutions As directed
Immunogen Synthesized human CD3 protein
Size and concentration 7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form liquid
Storage Instructions 2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity affinity purified
Clonality monoclonal
Isotype IgG1
Compatible secondaries goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486 goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854 goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706 goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control Mouse monoclonal IgG1 - Isotype Control

target relevance
Protein names Tumor necrosis factor receptor superfamily member 8 (CD30L receptor) (Ki-1 antigen) (Lymphocyte activation antigen CD30) (CD antigen CD30)
Gene names TNFRSF8,TNFRSF8 CD30 D1S166E
Protein family TNFR8 family
Mass 9606Da
Function Receptor for TNFSF8/CD30L (PubMed:8391931). May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (PubMed:8999898).
Subellular location [Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Cytoplasm .
Tissues [Isoform 2]: Detected in alveolar macrophages (at protein level).
Structure Interacts with TRAF1, TRAF2, TRAF3 and TRAF5.
Post-translational modification Phosphorylated on serine and tyrosine residues (Probable). Isoform 2 is constitutively phosphorylated (PubMed:8839832).
Target Relevance information above includes information from UniProt accession: P28908
The UniProt Consortium

Data

Human Hodgkin lymphoma stained with anti-CD30 antibody using peroxidase-conjugate and DAB chromogen. Note the membranous staining of Hodgkin's cells.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.