Immunohistochemistry (IHC) : Human Hodgkin lymphoma stained with anti-CD30 antibody using peroxidase-conjugate and DAB chromogen. Note the membranous staining of Hodgkin’s cells.

rabbit anti-CD30 monoclonal antibody (ZR248) 6084

$160.00 – $528.00

Antibody summary

Rabbit monoclonal to CD30
Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Reacts with: Human
Isotype:IgG
Control: Hodgkin lymphoma or anaplastic large cell lymphoma
Visualization: Cell membrane and cytoplasmic
0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted

SKU: 6084parent Category: antibody Tags: anatomy, CD30, Hematopathology

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgG
clonality	monoclonal
concentration	concentrate, predilute
applications	IHC
reactivity	human
available size	0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

rabbit anti-CD30 monoclonal antibody ZR248 6084
antibody
Database link:
human P28908
Tested applications
IHC
Recommended dilutions
Concentrated 1:100-200
Application Notes
Positive control: Hodgkin lymphoma or anaplastic large cell lymphoma
Immunogen
Recombinant human full-length TNFRSF8 protein (CD30)
Size and concentration
7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form
liquid
Storage Instructions
2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity
affinity purified
Clonality
monoclonal
Isotype
IgG
Compatible secondaries
goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863
goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720
Isotype control
Rabbit polyclonal - Isotype Control
target relevance
Protein names
Tumor necrosis factor receptor superfamily member 8 (CD30L receptor) (Ki-1 antigen) (Lymphocyte activation antigen CD30) (CD antigen CD30)
Gene names
TNFRSF8,TNFRSF8 CD30 D1S166E
Protein family
TNFR8 family
Mass
9606Da
Function
Receptor for TNFSF8/CD30L (PubMed:8391931). May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (PubMed:8999898).
Subellular location
[Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Cytoplasm .
Tissues
[Isoform 2]: Detected in alveolar macrophages (at protein level).
Structure
Interacts with TRAF1, TRAF2, TRAF3 and TRAF5.
Post-translational modification
Phosphorylated on serine and tyrosine residues (Probable). Isoform 2 is constitutively phosphorylated (PubMed:8839832).
Target Relevance information above includes information from UniProt accession: P28908
The UniProt Consortium

Human Hodgkin lymphoma stained with anti-CD30 antibody using peroxidase-conjugate and DAB chromogen. Note the membranous staining of Hodgkin's cells.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.