Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
host | mouse |
isotype | IgG |
clonality | monoclonal |
concentration | concentrate, predilute |
applications | IHC |
reactivity | human |
available size | 0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted |
rabbit anti-CD103 monoclonal antibody (ZR404) 6054
$160.00 – $528.00
Antibody summary
- Rabbit monoclonal to CD103
- Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
- Reacts with: Human
- Isotype:IgG
- Control: colon
- Visualization: Cell surface and cytoplasmic
- 0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted
rabbit anti-CD103 monoclonal antibody ZR404 6054
target relevance |
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Protein names Integrin alpha-E (HML-1 antigen) (Integrin alpha-IEL) (Mucosal lymphocyte 1 antigen) (CD antigen CD103) [Cleaved into: Integrin alpha-E light chain; Integrin alpha-E heavy chain] |
Protein family Integrin alpha chain family |
Mass 130159Da |
Function Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. |
Subellular location Membrane; Single-pass type I membrane protein. |
Tissues Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells. |
Structure Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of a heavy and a light chains linked by a disulfide bond. Alpha-E associates with beta-7. |
Domain DOMAIN 200..389; /note="VWFA"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00219" |
Target Relevance information above includes information from UniProt accession: P38570 |
The UniProt Consortium |
Data
Formalin-Fixed, paraffin-embedded human colon carcinoma stained with anti-CD103 antibody using peroxidase-conjugate and DAB chromogen. Note the cell surface staining of subset of T cells |
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.pmid | title | authors | citation |
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Protocols
relevant to this product |
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IHC |
Documents
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