Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
host | mouse |
isotype | IgG |
clonality | monoclonal |
concentration | concentrate, predilute |
applications | IHC |
reactivity | human |
available size | 0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted |
rabbit anti-OCT-2 monoclonal antibody (ZR227) 6297
$160.00 – $528.00
Antibody summary
- Rabbit monoclonal to OCT-2
- Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
- Reacts with: Human
- Isotype:IgG
- Control: B-cell lymphoma
- Visualization: Nuclear
- 0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted
rabbit anti-OCT-2 monoclonal antibody ZR227 6297
antibody |
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Database link: human P09086 |
Tested applications IHC |
Recommended dilutions As directed |
Immunogen A peptide corresponding to human NUT protein |
Size and concentration 7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated |
Form liquid |
Storage Instructions 2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles. |
Purity affinity purified |
Clonality monoclonal |
Isotype IgG |
Compatible secondaries goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863 goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720 |
Isotype control Rabbit polyclonal - Isotype Control |
target relevance |
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Protein names POU domain, class 2, transcription factor 2 (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2) (Octamer-binding protein 2) (Oct-2) (Octamer-binding transcription factor 2) (OTF-2) |
Protein family POU transcription factor family, Class-2 subfamily |
Mass 51209Da |
Function Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') (PubMed:2904654, PubMed:7859290). Regulates IL6 expression in B cells with POU2AF1 (By similarity). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression (PubMed:2901913, PubMed:2904654). Modulates transcription transactivation by NR3C1, AR and PGR (PubMed:10480874). .; [Isoform 5]: Activates the U2 small nuclear RNA (snRNA) promoter. . |
Subellular location Cytoplasm . Nucleus. |
Tissues Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147. . |
Structure Interacts with NR3C1, AR and PGR (PubMed:10480874). Interacts with POU2AF1; the interaction increases POU2F2 transactivation activity (PubMed:7859290). . |
Domain DOMAIN 195..269; /note="POU-specific"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00530" |
Target Relevance information above includes information from UniProt accession: P09086 |
The UniProt Consortium |
Data
Formalin-fixed, paraffin-embedded human lymph node stained with anti-OCT2 antibody using peroxidase-conjugate and DAB chromogen. Note nuclear staining of follicular B cells |
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.pmid | title | authors | citation |
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Protocols
relevant to this product |
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IHC |
Documents
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Please enter your product and batch number here to retrieve - product datasheet, SDS, and QC information. |
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