| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | mouse |
| isotype | IgG |
| clonality | monoclonal |
| concentration | concentrate, predilute |
| applications | IHC |
| reactivity | human |
| available size | 0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted |
rabbit anti-CD103 monoclonal antibody (ZR404) 6054
Price range: $160.00 through $528.00
Antibody summary
- Rabbit monoclonal to CD103
- Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
- Reacts with: Human
- Isotype:IgG
- Control: colon
- Visualization: Cell surface and cytoplasmic
- 0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted
rabbit anti-CD103 monoclonal antibody ZR404 6054
| target relevance |
|---|
| Protein names Integrin alpha-E (HML-1 antigen) (Integrin alpha-IEL) (Mucosal lymphocyte 1 antigen) (CD antigen CD103) [Cleaved into: Integrin alpha-E light chain; Integrin alpha-E heavy chain] |
| Gene names ITGAE,ITGAE |
| Protein family Integrin alpha chain family |
| Mass 130159Da |
| Function FUNCTION: Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. |
| Subellular location SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. |
| Tissues TISSUE SPECIFICITY: Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells. |
| Structure SUBUNIT: Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of a heavy and a light chains linked by a disulfide bond. Alpha-E associates with beta-7. |
| Domain DOMAIN: The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. |
| Target Relevance information above includes information from UniProt accession: P38570 |
| The UniProt Consortium |
Data
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| Formalin-Fixed, paraffin-embedded human colon carcinoma stained with anti-CD103 antibody using peroxidase-conjugate and DAB chromogen. Note the cell surface staining of subset of T cells |
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Protocols
| relevant to this product |
|---|
| IHC |
Documents
| # | SDS | Certificate | |
|---|---|---|---|
| Please enter your product and batch number here to retrieve product datasheet, SDS, and QC information. | |||
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