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Influenza A Virus IgM ELISA kit-SERION <i>classic</i> ESR1231M - Image 2

Influenza A Virus IgM ELISA kit-SERION <i>classic</i> ESR1231M - Image 3

Influenza A Virus IgM ELISA kit-SERION classic ESR1231M

$398.00

Summary

Virion/Serion Diagnostic Kit for research use (RUO)
Influenza A Virus IgM ELISA Kit
Suitable for IgM detection
Ready-to-use
96 tests

SKU: ESR1231M Category: Virion/Serion kits Tags: ELISA, IgM, Influenza Virus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Influenza A Virus reactive IgM
species reactivity	Influenza A Virus
applications	ELISA
assay type	Indirect & quantitative
available sizes	96 tests

Influenza A Virus IgM ELISA Kit ESR1231M

Assay type
Indirect ELISA

Research area
Infectious Disease

Sample type
Serum, plasma, whole blood

Notes
Pretreatment of samples with RF-Absorbent (Z200) is recommended for use with IgM ELISA kits to eliminate presence of sample rheumatoid factors and possible false negative results.

Components

Break apart microtiter test strips each with antigen coated single wells	8 x 12 (96 Total)
Standard serum (ready-to-use)	2 x 2 mL
Negative control serum (ready-to-use)	2 mL
Anti-human-IgM-conjugate (ready-to-use)	13 mL
Washing solution concentrate (sufficient for 1000ml)	33.3 mL
Dilution buffer	2 x 50 mL
Stopping solution	15 mL
Substrate (ready-to-use)	13 mL
Quality control certificate with standard curve and evaluation table	1

Storage
Store at 2 - 8°C until expiration on packaging.

Associated products
Influenza A Virus IgA Control Serum (BC1231A)
Influenza A Virus IgG Control Serum (BC1231G)
Influenza A Virus IgM Control Serum (BC1231M)
Influenza A Virus IgA ELISA Kit (ESR1231A)
Influenza A Virus IgG ELISA Kit (ESR1231G)
Influenza A Virus IgM ELISA Kit (ESR1231M)

target relevance

human antibody anti-Influenza Virus

Influenza Virus

Description
Virus that causes influenza (flu)

Structure
Influenza viruses are enveloped, negative-sense, single-stranded RNA viruses belonging to the Orthomyxoviridae family. The viral genome is segmented into multiple RNA molecules, allowing genetic reassortment between different strains. Influenza A and B viruses are the primary causes of seasonal influenza in humans, while Influenza A viruses also infect a wide range of animal species including birds, pigs, horses, and marine mammals. The viral envelope contains the surface glycoproteins hemagglutinin (HA) and neuraminidase (NA), which are responsible for viral attachment, entry, and release from host cells. Influenza viruses are characterized by a high mutation rate, resulting in antigenic drift and the emergence of new variants. Periodically, reassortment events between different influenza strains can result in antigenic shift, leading to the emergence of pandemic viruses.

Diagnosis
The diagnosis of influenza is performed by the detection of viral RNA, viral antigens, or influenza-specific antibodies. Molecular methods such as reverse transcription polymerase chain reaction (RT-PCR) are considered the gold standard for the detection and differentiation of influenza virus types and subtypes. Rapid influenza diagnostic tests (RIDTs) detect viral antigens and provide results within minutes but generally have lower sensitivity than molecular methods. Serological assays including ELISA and hemagglutination inhibition tests may be used to determine previous exposure, monitor immune responses, or support epidemiological investigations. Influenza-specific IgM antibodies typically appear during the acute phase of infection, while IgG antibodies develop later and may persist for years, providing varying degrees of immunity against related viral strains.

Symptoms
Influenza viruses are highly contagious respiratory pathogens that spread primarily through respiratory droplets and aerosols generated by infected individuals. Following an incubation period of approximately one to four days, influenza typically presents with abrupt onset of fever, chills, headache, myalgia, fatigue, sore throat, and dry cough. Additional symptoms may include nasal congestion, runny nose, and loss of appetite. Although most infections are self-limiting, severe disease can occur in young children, elderly individuals, pregnant women, and immunocompromised patients. Complications include viral pneumonia, secondary bacterial pneumonia, myocarditis, encephalitis, and acute respiratory distress syndrome (ARDS). Seasonal influenza is responsible for substantial morbidity and mortality worldwide, and periodic pandemics caused by novel influenza A strains can result in widespread outbreaks with significant public health impact.

Data

FAQ & Publications

Frequently Asked Questions

What sample types are compatible with the Influenza A Virus IgM ELISA Kit ESR1231M?

The Influenza A Virus IgM ELISA Kit ESR1231M is suitable for use with serum, plasma, and whole blood samples.

How should the Influenza A Virus IgM ELISA Kit be stored to maintain stability and performance?

The kit should be stored at 2 to 8°C until the expiration date indicated on the packaging to ensure optimal stability and performance.

Is there a recommended pretreatment step to improve assay specificity when using the Influenza A Virus IgM ELISA Kit?

Yes, pretreatment of samples with RF-Absorbent Z200 is recommended to remove IgM rheumatoid factors from serum and plasma samples, which helps eliminate possible false negative results and improves signal specificity.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
ESR1231M protocol

Documents

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Influenza A Virus IgM ELISA kit-SERION classic ESR1231M

RF-Absorbent Z200 for use with IgM ELISA kits

Data

FAQ & Publications

Protocols

Documents

Related Technical Resources & Posts

Reviews

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