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Oct2
Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates IL6 expression in B cells with POU2AF1 (By similarity). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR.; [Isoform 5]: Activates the U2 small nuclear RNA (snRNA) promoter.
| target | type | reactivity | applications | ||||
|---|---|---|---|---|---|---|---|
| 6297 | Oct2 | rabbit monoclonal | human | IHC | |||
| 6298 | Oct2 | mouse monoclonal | human | IHC | |||
IHC with antibody [6298] : Human lymph node stained with anti-OCT-2 antibody using peroxidase-conjugate and DAB chromogen. Note nuclear staining of follicular center B cells.
IHC with antibody [6296] : Formalin-fixed, paraffin-embedded human NUT carcinoma stained with anti-NUT antibody using peroxidase-conjugate and DAB chromogen. Note nuclear staining of tumor cells
