| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | mouse |
| isotype | IgG |
| clonality | monoclonal |
| concentration | concentrate, predilute |
| applications | IHC |
| reactivity | human |
| available size | 0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted |
rabbit anti-CD7 monoclonal antibody (ZR416) 6109
Price range: $160.00 through $528.00
Antibody summary
- Rabbit monoclonal to CD7
- Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
- Reacts with: Human
- Isotype:IgG
- Control: Tonsil or lymph node
- Visualization: Membrane
- 0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted
rabbit anti-CD7 monoclonal antibody ZR416 6109
| target relevance |
|---|
| Homo sapiens CD7 T-cell antigen CD7 |
| Protein names T-cell antigen CD7 |
| Alternative names GP40, T-cell leukemia antigen, T-cell surface antigen Leu-9, TP41 |
| Gene names CD7 |
| Function Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors (PubMed:7506726). Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1 (PubMed:10652336). In turn, mediates the production of cytokines such as IL-2 (PubMed:1709867). On resting NK-cells, CD7 activation results in a significant induction of interferon-gamma levels (PubMed:7506726) |
| Subcellular location Membrane |
| Structure Interacts with SECTM1 |
| Keywords Adaptive immunity, Disulfide bond, Glycoprotein, Immunity, Immunoglobulin domain, Lipoprotein, Membrane, Palmitate, Proteomics identification, Receptor, Reference proteome, Repeat, Signal, Transmembrane, Transmembrane helix |
| Sequence MAGPPRLLLLPLLLALARGLPGALAAQEVQQSPHCTTVPVGASVNITCSTSGGLRGIYLR QLGPQPQDIIYYEDGVVPTTDRRFRGRIDFSGSQDNLTITMHRLQLSDTGTYTCQAITEV NVYGSGTLVLVTEEQSQGWHRCSDAPPRASALPAPPTGSALPDPQTASALPDPPAASALP AALAVISFLLGLGLGVACVLARTQIKKLCSWRDKNSAACVVYEDMSHSRCNTLSSPNQYQ |
| UniProt accession: P09564 |
Data
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| Formalin-fixed paraffin-embedded human tonsil stained with anti-CD7antibody using peroxidase-conjugate and DAB chromogen. Note cell membrane staining of perifollicular T-cells cell |
FAQ & Publications
Frequently Asked Questions
What applications is the rabbit anti-CD7 monoclonal antibody (ZR416) validated for?
This antibody is validated for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded human tissues.
How should the rabbit anti-CD7 monoclonal antibody be stored to maintain its stability?
For short-term storage, keep the antibody at 2-8°C; for long-term storage, it should be kept at -20°C while avoiding repeated freeze/thaw cycles.
Is the rabbit anti-CD7 antibody reactive with species other than human?
This antibody specifically reacts with human CD7 and is not indicated for other species.
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.
Protocols
| relevant to this product |
|---|
| IHC |
Documents
| Batch Number | QC File | SDS |
|---|---|---|
| To view batch-specific Safety Datasheets and Quality Certificates associated with your account, please Log In. | ||
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