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rabbit anti-CD123 monoclonal antibody (ZR425) 6058

$160.00$528.00

Antibody summary

  • Rabbit monoclonal to CD123
  • Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
  • Reacts with: Human
  • Isotype:IgG
  • Control: Lymph node or thymus
  • Visualization: Cytoplasmic
  • 0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted
SKU: 6058parent Category: Tags: , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
host

mouse

isotype

IgG

clonality

monoclonal

concentration

concentrate, predilute

applications

IHC

reactivity

human

available size

0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

rabbit anti-CD123 monoclonal antibody ZR425 6058

antibody
Database link:
human O75794
Tested applications
IHC
Recommended dilutions
As directed
Immunogen
Recombinant fragment of human IL3RA protein (around aa 26-171)
Size and concentration
7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form
liquid
Storage Instructions
2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity
affinity purified
Clonality
monoclonal
Isotype
IgG
Compatible secondaries
goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863
goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720
Isotype control
Rabbit polyclonal - Isotype Control
target relevance
Protein names
Translation initiation factor eIF2 assembly protein (Cell division cycle protein 123 homolog) (Protein D123) (HT-1080) (PZ32)
Protein family
CDC123 family
Mass
39135Da
Function
ATP-dependent protein-folding chaperone for the eIF2 complex (PubMed:35031321, PubMed:37507029). Binds to the gamma subunit of the eIF2 complex which allows the subunit to assemble with the alpha and beta subunits (By similarity).
Subellular location
Cytoplasm .
Tissues
Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes with the highest expression in testis.
Structure
Interacts with the eIF2 complex gamma subunit EIF2S3 (via C-terminus); the interaction is direct (PubMed:35031321, PubMed:37507029). Interacts with the eIF2 complex alpha subunit EIF2S1 (PubMed:31836389, PubMed:35031321). Interacts with the eIF2 complex beta subunit EIF2S2 (PubMed:31836389, PubMed:35031321).
Target Relevance information above includes information from UniProt accession: O75794
The UniProt Consortium

Data

Human tonsil stained with anti-CD123 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of plasmacytoid dendritic cells.
Human tonsil stained with anti-CD123 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of plasmacytoid dendritic cells.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




pmidtitleauthorscitation

Protocols

relevant to this product
IHC

Documents

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