Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
host | mouse |
isotype | IgG |
clonality | monoclonal |
concentration | concentrate, predilute |
applications | IHC |
reactivity | human |
available size | 0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted |
rabbit anti-CD123 monoclonal antibody (ZR425) 6058
$160.00 – $528.00
Antibody summary
- Rabbit monoclonal to CD123
- Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
- Reacts with: Human
- Isotype:IgG
- Control: Lymph node or thymus
- Visualization: Cytoplasmic
- 0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted
rabbit anti-CD123 monoclonal antibody ZR425 6058
target relevance |
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Protein names Translation initiation factor eIF2 assembly protein (Cell division cycle protein 123 homolog) (Protein D123) (HT-1080) (PZ32) |
Protein family CDC123 family |
Mass 39135Da |
Function ATP-dependent protein-folding chaperone for the eIF2 complex (PubMed:35031321, PubMed:37507029). Binds to the gamma subunit of the eIF2 complex which allows the subunit to assemble with the alpha and beta subunits (By similarity). |
Subellular location Cytoplasm . |
Tissues Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes with the highest expression in testis. |
Structure Interacts with the eIF2 complex gamma subunit EIF2S3 (via C-terminus); the interaction is direct (PubMed:35031321, PubMed:37507029). Interacts with the eIF2 complex alpha subunit EIF2S1 (PubMed:31836389, PubMed:35031321). Interacts with the eIF2 complex beta subunit EIF2S2 (PubMed:31836389, PubMed:35031321). |
Target Relevance information above includes information from UniProt accession: O75794 |
The UniProt Consortium |
Data
Human tonsil stained with anti-CD123 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of plasmacytoid dendritic cells. |
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.pmid | title | authors | citation |
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Protocols
relevant to this product |
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IHC |
Documents
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