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Parvovirus IgM ELISA kit-SERION classic ESR122M

$398.00

Summary

Virion/Serion Diagnostic Kit for research use (RUO)
Parvovirus IgM ELISA Kit
Suitable for IgM detection
Ready-to-use
96 tests

SKU: ESR122M Category: Virion/Serion kits Tags: ELISA, IgM, Parvovirus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Parvovirus reactive IgM
species reactivity	Parvovirus
applications	ELISA
assay type	Indirect & quantitative
available sizes	96 tests

Parvovirus IgM ELISA Kit ESR122M

Assay type
Indirect ELISA

Research area
Infectious Disease

Sample type
Serum, plasma, whole blood

Notes
Pretreatment of samples with RF-Absorbent (Z200) is recommended for use with IgM ELISA kits to eliminate presence of sample rheumatoid factors and possible false negative results.

Components

Break apart microtiter test strips each with antigen coated single wells	8 x 12 (96 Total)
Standard serum (ready-to-use)	2 x 2 mL
Negative control serum (ready-to-use)	2 mL
Anti-human-IgM-conjugate (ready-to-use)	13 mL
Washing solution concentrate (sufficient for 1000ml)	33.3 mL
Dilution buffer	2 x 50 mL
Stopping solution	15 mL
Substrate (ready-to-use)	13 mL
Quality control certificate with standard curve and evaluation table	1

Storage
Store at 2-8°C.

target relevance

human antibody anti-Parvovirus

Parvovirus

Description
Group of viruses that cause gastrointestinal, respiratory, and systemic infections in humans and animals

Structure
Parvoviruses are small, non-enveloped viruses containing a linear single-stranded DNA genome and belonging to the family Parvoviridae. The viral capsid possesses an icosahedral structure and lacks a lipid envelope, contributing to exceptional environmental stability and resistance to many common disinfectants. Members of the Parvoviridae family infect a wide range of vertebrate and invertebrate hosts and include important human and veterinary pathogens. Human Parvovirus B19 is the best-known human pathogen of the group and is the causative agent of erythema infectiosum (fifth disease). Other parvoviruses, such as canine parvovirus and feline panleukopenia virus, cause severe disease in animals. Parvoviruses preferentially infect rapidly dividing cells because they rely on host cellular machinery for viral DNA replication.

Diagnosis
The diagnosis of parvovirus infection depends on the specific virus involved and may include serological, molecular, and antigen detection methods. Human Parvovirus B19 infection is commonly diagnosed through the detection of virus-specific IgM and IgG antibodies or by polymerase chain reaction (PCR) assays that identify viral DNA in blood or tissue samples. In veterinary medicine, infections such as canine parvovirus are frequently diagnosed using ELISA-based antigen detection tests on fecal samples, while PCR provides highly sensitive confirmation and strain identification. Laboratory findings and clinical presentation are often used in conjunction with specific diagnostic tests to establish the diagnosis.

Symptoms
Parvovirus infections produce a broad spectrum of clinical manifestations depending on the host species and the specific virus involved. Human Parvovirus B19 infection commonly causes erythema infectiosum, characterized by a distinctive 'slapped-cheek' rash, mild fever, headache, and malaise. In adults, joint pain and arthritis-like symptoms may occur. In immunocompromised individuals or patients with underlying hematological disorders, severe anemia may develop due to infection of erythroid precursor cells. During pregnancy, fetal infection may result in hydrops fetalis or fetal loss. Animal parvoviruses, particularly canine parvovirus, commonly cause severe gastrointestinal disease characterized by vomiting, hemorrhagic diarrhea, dehydration, lethargy, and potentially fatal secondary infections.

Data

FAQ & Publications

Frequently Asked Questions

What is the primary application of the Parvovirus IgM ELISA Kit ESR122M?

The Parvovirus IgM ELISA Kit ESR122M is designed for the indirect and quantitative detection of Parvovirus reactive IgM antibodies in serum, plasma, and whole blood samples, primarily for research use in infectious disease studies.

How should samples be pretreated when using this IgM ELISA kit to improve assay specificity?

It is recommended to pretreat samples with RF-Absorbent Z200 to remove IgM rheumatoid factors from serum and plasma samples, thereby reducing possible false negative results and improving signal specificity in the detection of pathogen-specific IgM.

What are the storage conditions for the Parvovirus IgM ELISA Kit ESR122M?

The kit should be stored at refrigerated temperatures between 2 to 8 degrees Celsius to maintain reagent stability and assay performance.

How many tests are included in one Parvovirus IgM ELISA Kit ESR122M package?

One kit contains 96 tests, provided as eight strips of twelve antigen-coated wells each, along with all necessary reagents and controls.

Is the Parvovirus IgM ELISA Kit ESR122M suitable for detecting antibodies against human parvovirus B19?

Yes, the kit targets Parvovirus B19 reactive IgM antibodies, which are indicative of infection with human parvovirus B19, the causative agent of conditions such as erythema infectiosum.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
ESR122M protocol

Documents

#
EQ0077	Safety Data Sheet	QC certificate

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Parvovirus IgM ELISA kit-SERION classic ESR122M

RF-Absorbent Z200 for use with IgM ELISA kits

Data

FAQ & Publications

Protocols

Documents

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Reviews

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