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Mumps Virus IgM ELISA kit-SERION classic ESR103M

$398.00

Summary

Virion/Serion Diagnostic Kit for research use (RUO)
Mumps Virus IgM ELISA Kit
Suitable for IgM detection
Ready-to-use
96 tests

SKU: ESR103M Category: Virion/Serion kits Tags: ELISA, IgM, Mumps Virus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Mumps Virus reactive IgM
species reactivity	Mumps Virus
applications	ELISA
assay type	Indirect & quantitative
available sizes	96 tests

Mumps Virus IgM ELISA Kit ESR103M

Assay type
Indirect ELISA

Research area
Infectious Disease

Sample type
Serum, plasma, whole blood

Notes
Pretreatment of samples with RF-Absorbent (Z200) is recommended for use with IgM ELISA kits to eliminate presence of sample rheumatoid factors and possible false negative results.

Components

Break apart microtiter test strips each with antigen coated single wells	8 x 12 (96 Total)
Standard serum (ready-to-use)	2 x 2 mL
Negative control serum (ready-to-use)	2 mL
Anti-human-IgM-conjugate (ready-to-use)	13 mL
Washing solution concentrate (sufficient for 1000ml)	33.3 mL
Dilution buffer	2 x 50 mL
Stopping solution	15 mL
Substrate (ready-to-use)	13 mL
Quality control certificate with standard curve and evaluation table	1

Storage
Store at 2-8°C.

Associated products
Mumps Virus Nucleoprotein Control Antigen (BA103R01)
Mumps Virus Antigen (BA103VS)
Mumps/Parotitis Virus IgG Control Serum (BC103G)
Mumps/Parotitis Virus IgM Control Serum (BC103M)
Mumps Virus IgG ELISA Kit (ESR103G)
Mumps Virus IgM ELISA Kit (ESR103M)

target relevance

human antibody anti-Mumps Virus

Mumps Virus

Description
Virus that causes mumps (epidemic parotitis)

Structure
Mumps virus is an enveloped, negative-sense, single-stranded RNA virus belonging to the genus Orthorubulavirus within the family Paramyxoviridae. Humans are the only known natural host of the virus. The viral particle is surrounded by a lipid envelope containing surface glycoproteins responsible for attachment to and entry into host cells. Mumps virus is transmitted primarily through respiratory droplets, saliva, and direct contact with infected individuals. Following infection, the virus initially replicates in the upper respiratory tract and regional lymphoid tissues before spreading through the bloodstream to multiple organs, particularly the salivary glands, testes, ovaries, pancreas, and central nervous system. Although widespread vaccination has significantly reduced the incidence of mumps in many countries, outbreaks continue to occur, particularly in settings involving close contact such as schools, universities, and military facilities.

Diagnosis
The diagnosis of mumps virus infection is performed through serological and molecular methods. Detection of mumps-specific IgM antibodies by ELISA is commonly used to support the diagnosis of recent infection, while IgG testing may be used to assess immune status or prior exposure. Reverse transcription polymerase chain reaction (RT-PCR) is the preferred method for laboratory confirmation and allows sensitive detection of viral RNA in buccal swabs, saliva, cerebrospinal fluid, and other clinical specimens. Viral culture may be performed in specialized laboratories but is less commonly used due to the availability of rapid molecular techniques. Laboratory confirmation is particularly important because mumps can resemble other causes of parotitis and viral illness.

Symptoms
Mumps virus infection typically develops following an incubation period of approximately twelve to twenty-five days. Early symptoms commonly include fever, headache, fatigue, muscle aches, loss of appetite, and malaise. The most characteristic feature of the disease is painful swelling of one or both parotid salivary glands, resulting in facial swelling and tenderness near the jaw and ears. Additional salivary glands may also be affected. While many infections are mild or asymptomatic, complications can occur and may include orchitis, epididymitis, oophoritis, mastitis, pancreatitis, meningitis, encephalitis, and hearing loss. In post-pubertal males, orchitis may occasionally result in testicular atrophy and impaired fertility. Although most patients recover completely, severe neurological complications can occur in rare cases.

Data

FAQ & Publications

Frequently Asked Questions

What type of antibody detection does the Mumps Virus IgM ELISA Kit ESR103M perform?

The Mumps Virus IgM ELISA Kit ESR103M is designed for indirect and quantitative detection of Mumps Virus reactive IgM antibodies.

Which sample types are compatible with this ELISA kit for detecting Mumps Virus IgM?

The kit is suitable for use with serum, plasma, and whole blood samples.

Is there a recommended pretreatment step to improve assay specificity when using this IgM ELISA kit?

Yes, pretreatment of samples with RF-Absorbent Z200 is recommended to eliminate rheumatoid factors from serum and plasma samples, which helps reduce false negative results and improves signal specificity.

How should the Mumps Virus IgM ELISA Kit be stored to maintain its stability and performance?

The kit components should be stored at 2-8°C to ensure stability and optimal performance.

What components are included in the Mumps Virus IgM ELISA Kit ESR103M for conducting 96 tests?

The kit includes break-apart microtiter test strips with antigen-coated wells, standard and negative control sera, anti-human-IgM conjugate, washing solution concentrate, dilution buffer, stopping solution, substrate, and a quality control certificate with standard curve and evaluation table.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
ESR103M protocol

Documents

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Mumps Virus IgM ELISA kit-SERION classic ESR103M

RF-Absorbent Z200 for use with IgM ELISA kits

Data

FAQ & Publications

Protocols

Documents

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Reviews

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