| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| target | Mumps Virus Nucleoprotein |
| species reactivity | Mumps Virus |
| applications | ELISA |
| assay type | Indirect & quantitative |
| available size | 1 mg |
Mumps Virus Nucleoprotein Control Antigen BA103R01
$944.00
Summary
- Virion/Serion Diagnostic Kit Control for research use (RUO)
- Mumps Virus Nucleoprotein Control Antigen, recombinant
- Suitable for detection of IgA, IgG & IgM antibodies in ELISA
- Lot specific concentration, specified in mg/mL
- 1 mg
Mumps Virus Nucleoprotein Control Antigen BA103R01
| kit |
|---|
| Research area Infectious Disease |
| Storage Store at -65°C. Avoid freeze/thaw cycles. Sonicate before use. |
| Form liquid |
| Associated products Mumps Virus Nucleoprotein Control Antigen (BA103R01) Mumps Virus Antigen (BA103VS) Mumps/Parotitis Virus IgG Control Serum (BC103G) Mumps/Parotitis Virus IgM Control Serum (BC103M) Mumps Virus IgG ELISA Kit (ESR103G) Mumps Virus IgM ELISA Kit (ESR103M) |
| target relevance |
|---|
| Mumps Virus |
| Description Virus that causes mumps (epidemic parotitis) |
| Structure Mumps virus is an enveloped, negative-sense, single-stranded RNA virus belonging to the genus Orthorubulavirus within the family Paramyxoviridae. Humans are the only known natural host of the virus. The viral particle is surrounded by a lipid envelope containing surface glycoproteins responsible for attachment to and entry into host cells. Mumps virus is transmitted primarily through respiratory droplets, saliva, and direct contact with infected individuals. Following infection, the virus initially replicates in the upper respiratory tract and regional lymphoid tissues before spreading through the bloodstream to multiple organs, particularly the salivary glands, testes, ovaries, pancreas, and central nervous system. Although widespread vaccination has significantly reduced the incidence of mumps in many countries, outbreaks continue to occur, particularly in settings involving close contact such as schools, universities, and military facilities. |
| Diagnosis The diagnosis of mumps virus infection is performed through serological and molecular methods. Detection of mumps-specific IgM antibodies by ELISA is commonly used to support the diagnosis of recent infection, while IgG testing may be used to assess immune status or prior exposure. Reverse transcription polymerase chain reaction (RT-PCR) is the preferred method for laboratory confirmation and allows sensitive detection of viral RNA in buccal swabs, saliva, cerebrospinal fluid, and other clinical specimens. Viral culture may be performed in specialized laboratories but is less commonly used due to the availability of rapid molecular techniques. Laboratory confirmation is particularly important because mumps can resemble other causes of parotitis and viral illness. |
| Symptoms Mumps virus infection typically develops following an incubation period of approximately twelve to twenty-five days. Early symptoms commonly include fever, headache, fatigue, muscle aches, loss of appetite, and malaise. The most characteristic feature of the disease is painful swelling of one or both parotid salivary glands, resulting in facial swelling and tenderness near the jaw and ears. Additional salivary glands may also be affected. While many infections are mild or asymptomatic, complications can occur and may include orchitis, epididymitis, oophoritis, mastitis, pancreatitis, meningitis, encephalitis, and hearing loss. In post-pubertal males, orchitis may occasionally result in testicular atrophy and impaired fertility. Although most patients recover completely, severe neurological complications can occur in rare cases. |
Data
FAQ & Publications
Frequently Asked Questions
What is the recommended storage condition for the Mumps Virus Nucleoprotein Control Antigen BA103R01?
The Mumps Virus Nucleoprotein Control Antigen BA103R01 should be stored at -65°C and freeze/thaw cycles should be avoided to maintain its stability. It is recommended to sonicate the antigen before use.
For which immunoglobulin classes is the Mumps Virus Nucleoprotein Control Antigen BA103R01 suitable for detection in ELISA assays?
This recombinant control antigen is suitable for the detection of IgA, IgG, and IgM antibodies in ELISA assays.
Publications
| pmid | title | authors | citation |
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| We haven't added any publications to our database yet. | |||
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.
Protocols
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