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mouse anti-CD1a monoclonal antibody (O10) 6069

Price range: $160.00 through $528.00

Antibody summary

  • Mouse monoclonal to CD1a
  • Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
  • Reacts with: Human
  • Isotype:IgG1
  • Control: Skin or Langerhans cell histiocytosis X
  • Visualization: Cell membrane and cytoplasmic
  • 0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted
SKU: 6069parent Categories: , Tags: , ,
Weight 1 lbs
Dimensions 9 × 5 × 2 in
host

mouse

isotype

IgG1

clonality

monoclonal

concentration

concentrate, predilute

applications

IHC

reactivity

human

available size

0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

mouse anti-CD1a monoclonal antibody O10 6069

antibody
Database link:
human P06126
Tested applications
IHC
Recommended dilutions
Concentrated 1:50-100
Application Notes
Positive control: Skin or Langerhans cell histiocytosis X
Immunogen
CD1a
Size and concentration
7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form
liquid
Storage Instructions
2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity
affinity purified
Clonality
monoclonal
Isotype
IgG1
Compatible secondaries
goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486
goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685
goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854
goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706
goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716
goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control
Mouse monoclonal IgG1 - Isotype Control
target relevance
Homo sapiens CD1A
T-cell surface glycoprotein CD1a
Protein names
T-cell surface glycoprotein CD1a
Alternative names
T-cell surface antigen T6/Leu-6
Gene names
CD1A
Function
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells
Subcellular location
Cell membrane, Membrane raft, Endosome membrane
Structure
Heterodimer with B2M (beta-2-microglobulin). Interacts with CD74
Keywords
3D-structure, Adaptive immunity, Cell membrane, Disulfide bond, Endosome, Glycoprotein, Immunity, Immunoglobulin domain, Membrane, Proteomics identification, Reference proteome, Signal, Transmembrane, Transmembrane helix
Sequence
MLFLLLPLLAVLPGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDSN SSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCE LHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLS DTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRG EQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSSV GFIILAVIVPLLLLIGLALWFRKRCFC
UniProt accession: P06126

Data

Human skin stained with anti-CD1a antibody using peroxidase-conjugate and DAB chromogen. Note membrane staining of langerhan cells.
Human skin stained with anti-CD1a antibody using peroxidase-conjugate and DAB chromogen. Note membrane staining of langerhan cells.

FAQ & Publications

Frequently Asked Questions
What species does the mouse anti-CD1a monoclonal antibody (O10) react with?
This antibody specifically reacts with human CD1a antigen.
Which applications is the mouse anti-CD1a monoclonal antibody (O10) validated for?
It is validated for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded tissues.
How should the mouse anti-CD1a antibody be stored to maintain stability?
For short-term storage, keep the antibody at 2-8°C. For long-term storage, freeze at -20°C and avoid freeze/thaw cycles.
What is the recommended dilution for using the concentrated form of this antibody in IHC?
The concentrated antibody should be diluted between 1:50 and 1:100 for immunohistochemistry applications.
What controls are recommended when using the mouse anti-CD1a monoclonal antibody (O10) in experiments?
Skin tissue or Langerhans cell histiocytosis X samples are recommended as positive controls for this antibody.
Publications
pmid title authors citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
IHC

Documents

Batch Number QC File SDS
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