Measles Virus Nucleoprotein Control Antigen BA102R01

$944.00

Summary

Virion/Serion Diagnostic Kit Control for research use (RUO)
Measles Virus Nucleoprotein Control Antigen, recombinant
Suitable for detection of IgA, IgG & IgM antibodies in ELISA
Lot specific concentration, specified in mg/mL
1 mg

SKU: BA102R01 Category: Infectious disease proteins Tags: antigen, Measles Virus, protein

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Measles Virus Nucleoprotein
species reactivity	Measles Virus
applications	ELISA
assay type	Indirect & quantitative
available size	1 mg

Measles Virus Nucleoprotein Control Antigen BA102R01

kit
Research area Infectious Disease
Storage Store at -65°C. Avoid freeze/thaw cycles. Sonicate before use.
Form liquid
Associated products Measles Antigen (BA102VS) Measles Virus IgG ELISA Kit (ESR102G) Measles Virus IgM ELISA Kit (ESR102M) Measles Virus IgM Control Serum (BC102M) Measles Antigen [premium] (BA102VS-S)

target relevance
Measles Virus
Description Virus that causes measles (rubeola)
Structure Measles virus is an enveloped, negative-sense, single-stranded RNA virus belonging to the genus Morbillivirus within the family Paramyxoviridae. Humans are the only known natural reservoir of the virus. The viral particle contains a lipid envelope with fusion (F) and hemagglutinin (H) glycoproteins that mediate attachment to and entry into host cells. Measles virus is one of the most contagious human pathogens known and is transmitted primarily through respiratory droplets and airborne aerosols. Following infection, the virus initially replicates in the respiratory tract and regional lymphoid tissues before disseminating systemically. Measles virus can induce transient but profound immune suppression, increasing susceptibility to secondary infections for weeks to months after recovery. Widespread vaccination has dramatically reduced disease incidence in many regions, although outbreaks continue to occur where vaccination coverage is insufficient.
Diagnosis The diagnosis of measles virus infection is performed through serological and molecular methods. Detection of measles-specific IgM antibodies by ELISA is commonly used to confirm recent infection, while IgG antibody testing may be used to assess immune status or evidence of prior exposure. Reverse transcription polymerase chain reaction (RT-PCR) provides highly sensitive detection of viral RNA in respiratory specimens, throat swabs, nasopharyngeal samples, urine, and blood and is particularly useful during the early phase of infection. Viral genotyping may be performed for epidemiological investigations and outbreak surveillance. Laboratory confirmation is important because clinical symptoms can resemble those of other viral exanthematous illnesses.
Symptoms Measles virus infection typically develops following an incubation period of approximately seven to fourteen days. Early symptoms include high fever, cough, coryza (runny nose), conjunctivitis, malaise, and characteristic Koplik spots on the oral mucosa. Several days later, a maculopapular rash appears, beginning on the face and spreading downward to the trunk and extremities. Additional symptoms may include headache, fatigue, loss of appetite, and lymphadenopathy. Although most individuals recover completely, severe complications can occur, particularly in young children, malnourished individuals, pregnant women, and immunocompromised patients. Complications include otitis media, pneumonia, diarrhea, encephalitis, and the rare but fatal neurological disorder subacute sclerosing panencephalitis (SSPE). Measles remains a significant cause of vaccine-preventable morbidity and mortality worldwide.

Data

FAQ & Publications

Frequently Asked Questions

What is the primary application of the Measles Virus Nucleoprotein Control Antigen BA102R01?

This control antigen is primarily used for the detection of IgA, IgG, and IgM antibodies in indirect and quantitative ELISA assays.

How should the Measles Virus Nucleoprotein Control Antigen BA102R01 be stored to maintain stability?

The antigen should be stored at -65°C, avoiding freeze/thaw cycles, and sonicated before use to ensure proper dispersion.

Is the Measles Virus Nucleoprotein Control Antigen BA102R01 reactive across different measles virus genotypes?

Yes, despite multiple genotypes of measles virus, there is only one serotype. Antibodies bind to the hemagglutinin protein, so this antigen is suitable for detecting antibodies against all genotypes.

What is the concentration information provided for the Measles Virus Nucleoprotein Control Antigen BA102R01?

The product is supplied with a lot-specific concentration, which is specified in mg/mL on the product label.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.