Measles Virus (Premium) Antigen BA102VS-S

$865.00

Summary

Virion/Serion Immunologics Antigen for research use (RUO)
Measles Virus (Premium) Antigen, recombinant
Suitable for detection of IgA, IgG & IgM antibodies in ELISA
Lot specific concentration, specified in mg/mL
1 mg

SKU: BA102VS-S Category: Infectious disease proteins Tags: antigen, Measles Virus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Human Measles Virus Antigen
species reactivity	Measles Virus
applications	ELISA
assay type	Indirect & quantitative
available size	1 mg

Measles Virus (Premium) Antigen BA102VS-S

kit
Overview The native Measles Virus Antigen Premium (BA102VS-S) is produced by cultivation of measles virus (strain Edmonston) in Vero cells and a subsequent concentration of the culture supernatant by ultra-filtration and ultra-centrifugation. The resulting antigen preparation consists of a high concentration of virus and viral components that enable very sensitive and specific detection of IgG and IgM antibodies.
Research area Infectious Disease
Storage Store at -65µC. Avoid freeze/thaw cycles. Sonicate before use.
Form liquid
Associated products Measles Antigen (BA102VS) Measles Virus IgG Control Serum (BC102G) Measles Virus IgG ELISA Kit (ESR102G) Measles Virus IgM ELISA Kit (ESR102M) Measles Virus IgM Control Serum (BC102M)
Additional information Additional Serion Kit Information

target relevance
Measles Virus
Description Virus that causes measles (rubeola)
Structure Measles virus is an enveloped, negative-sense, single-stranded RNA virus belonging to the genus Morbillivirus within the family Paramyxoviridae. Humans are the only known natural reservoir of the virus. The viral particle contains a lipid envelope with fusion (F) and hemagglutinin (H) glycoproteins that mediate attachment to and entry into host cells. Measles virus is one of the most contagious human pathogens known and is transmitted primarily through respiratory droplets and airborne aerosols. Following infection, the virus initially replicates in the respiratory tract and regional lymphoid tissues before disseminating systemically. Measles virus can induce transient but profound immune suppression, increasing susceptibility to secondary infections for weeks to months after recovery. Widespread vaccination has dramatically reduced disease incidence in many regions, although outbreaks continue to occur where vaccination coverage is insufficient.
Diagnosis The diagnosis of measles virus infection is performed through serological and molecular methods. Detection of measles-specific IgM antibodies by ELISA is commonly used to confirm recent infection, while IgG antibody testing may be used to assess immune status or evidence of prior exposure. Reverse transcription polymerase chain reaction (RT-PCR) provides highly sensitive detection of viral RNA in respiratory specimens, throat swabs, nasopharyngeal samples, urine, and blood and is particularly useful during the early phase of infection. Viral genotyping may be performed for epidemiological investigations and outbreak surveillance. Laboratory confirmation is important because clinical symptoms can resemble those of other viral exanthematous illnesses.
Symptoms Measles virus infection typically develops following an incubation period of approximately seven to fourteen days. Early symptoms include high fever, cough, coryza (runny nose), conjunctivitis, malaise, and characteristic Koplik spots on the oral mucosa. Several days later, a maculopapular rash appears, beginning on the face and spreading downward to the trunk and extremities. Additional symptoms may include headache, fatigue, loss of appetite, and lymphadenopathy. Although most individuals recover completely, severe complications can occur, particularly in young children, malnourished individuals, pregnant women, and immunocompromised patients. Complications include otitis media, pneumonia, diarrhea, encephalitis, and the rare but fatal neurological disorder subacute sclerosing panencephalitis (SSPE). Measles remains a significant cause of vaccine-preventable morbidity and mortality worldwide.

Data

FAQ & Publications

Frequently Asked Questions

What type of antibodies can be detected using the Measles Virus (Premium) Antigen BA102VS-S in ELISA assays?

This antigen is suitable for the detection of IgA, IgG, and IgM antibodies in ELISA applications.

How should the Measles Virus (Premium) Antigen BA102VS-S be stored to maintain its stability?

The antigen should be stored at -65°C and freeze/thaw cycles should be avoided. Additionally, sonication before use is recommended.

What is the source and preparation method of the Measles Virus (Premium) Antigen BA102VS-S?

The antigen is produced by cultivation of the measles virus (strain Edmonston) in Vero cells, followed by concentration of the culture supernatant through ultra-filtration and ultra-centrifugation.

Which species' antibodies is the Measles Virus (Premium) Antigen BA102VS-S reactive with?

This antigen targets the Measles Virus and is reactive with human antibodies against the measles virus.

What is the typical application type and assay format recommended for the Measles Virus (Premium) Antigen BA102VS-S?

The antigen is used in indirect and quantitative ELISA assays for sensitive and specific detection of measles virus antibodies.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.