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Measles Virus Antigen BA102VS

$913.00

Summary

  • Virion/Serion Immunologics Antigen for research use (RUO)
  • Measles Virus Antigen, recombinant
  • Suitable for detection of IgA, IgG & IgM antibodies in ELISA
  • Lot specific concentration, specified in mg/mL
  • 1 mg
Weight1 lbs
Dimensions9 × 5 × 2 in
target

Human Measles Virus Antigen

species reactivity

Measles Virus

applications

ELISA

assay type

Indirect & quantitative

available size

1 mg

Available product – Measles Virus Antigen BA102VS

kit
Overview
Culture supernatant of measles virus infected cells is concentrated by ultrafiltration and ultracentrifugation. The resulting antigen preparation consists of a high concentration of virus and viral components and contains residual host cell material. The antigen is presented in 100 mM glycine buffer, pH 9.5.
Research area
Infectious Disease
Storage
Store at -65°C or lower. Avoid repeated freeze-thaw cycles. Sonicate before use. 10 years from date of manufacture (under recommended storage conditions).
Form
liquid
Associated products
Measles Virus IgG Control Serum (BC102G)
Measles Virus IgG ELISA Kit (ESR102G)
Measles Virus IgM ELISA Kit (ESR102M)
Measles Virus IgM Control Serum (BC102M)
Measles Antigen [premium] (BA102VS-S)
Additional information
Additional Serion Kit Information
target relevance
Organism
Measles morbillivirus (MeV)
Structure and strains
The measles virus genome is typically 15,894 nucleotides long and encodes eight proteins. The WHO currently recognises 8 clades of measles (A–H). Subtypes are designed with numerals—A1, D2 etc. Currently, 23 subtypes are recognised. The 450 nucleotides that code for the C‐terminal 150 amino acids of N are the minimum amount of sequence data required for genotyping a measles virus isolate.

Despite the variety of measles genotypes, there is only one measles serotype. Antibodies to measles bind to the hemagglutinin protein. Thus, antibodies against one genotype (such as the vaccine strain) protect against all other genotypes.

Disease
Measles Viruses occur worldwide and belong to the family of paramyxoviridae. The pathogen is transmitted by close contact with infected individuals primarily by droplet infection. Due to the high infectivity of the virus, measles is usually aquired during childhood.

After an incubation period of 10 to 12 days Koplik´s spots typically appear on oral mucosa in 60 to 70% of cases. In the course of the prodromal period flu-like symptoms may escalate until the typical measles exanthema arises with sharply increasing fever. The exanthema spreads from face to the extremities. The clinical symptoms peak within several days with a corresponding rapid recovery. Complications occur frequently, mainly pneumonia and encephalitis. Infection results in a life-long immunity. A combination of attenuated life vaccines for mumps, measles and rubella (MMR) has been available for several years.
Detection and diagnosis
Demonstration of IgM antibodies is commonly used as evidence for an acute infection and provides positive test results early on with the onset of symptoms. The demonstration of IgG antibodies serves primarily for immune status and vaccination control as well as for confirmation of Measles Virus infections. The detection of IgG antibodies in CSF samples is particularly recommended in cases of suspected encephalitis and multiple sclerosis.

Data

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

pmidtitleauthorscitation

Protocols

relevant to this product

Documents

Product data sheet
BA102VS

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