$A wide range of infectious disease ELISA kits and reagents made by Virion\Serion is available from benchmark antibodies$

Measles Virus IgM ELISA kit-SERION classic ESR102M

$364.00

Summary

Virion/Serion Diagnostic Kit for research use (RUO)
Measles Virus IgM ELISA Kit
Suitable for IgM detection
Ready-to-use
96 tests

SKU: ESR102M Category: Virion/Serion kits Tags: ELISA, Measles Virus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Human Measles Virus reactive IgM
species reactivity	Measles Virus
applications	ELISA
assay type	Indirect & quantitative
available sizes	96 tests

Measles Virus IgM ELISA Kit ESR102M

Assay type
Indirect ELISA

Overview
The SERION ELISA classic Masern/Measles Virus IgG and IgM tests are quantitative and qualitative immunoassays for the detection of human antibodies in serum or plasma directed against Measles Virus. The SERION ELISA classic Masern/Measles Virus IgM test is recommended for the determination of acute infections. The SERION ELISA classic Masern/Measles Virus IgG assay is recommended for determination of immune status and for detection of intrathecal synthesized IgG antibodies in cerebrospinal fluid for CSF diagnostics.

Research area
Infectious Disease

Sample type
Serum, plasma, whole blood

Notes
Pretreatment of samples with RF-Absorbent (Z200) is recommended for use with IgM ELISA kits to eliminate presence of sample rheumatoid factors and possible false negative results.

Components

Break apart microtiter test strips each with antigen coated single wells	8 x 12 (96 Total)
Standard serum (ready-to-use)	2 x 2 mL
Negative control serum (ready-to-use)	2 mL
Anti-human-IgM-conjugate (ready-to-use)	13 mL
Washing solution concentrate (sufficient for 1000ml)	33.3 mL
Dilution buffer	2 x 50 mL
Stopping solution	15 mL
Substrate (ready-to-use)	13 mL
Quality control certificate with standard curve and evaluation table	1

Storage
2-8°C

Associated products
Measles Antigen (BA102VS)
Measles Virus IgG Control Serum (BC102G)
Measles Virus IgG ELISA Kit (ESR102G)
Measles Virus IgM Control Serum (BC102M)
Measles Antigen [premium] (BA102VS-S)

Additional information
Additional Serion Kit Information

target relevance

human antibody anti-Measles Virus

Measles Virus

Description
Virus that causes measles (rubeola)

Structure
Measles virus is an enveloped, negative-sense, single-stranded RNA virus belonging to the genus Morbillivirus within the family Paramyxoviridae. Humans are the only known natural reservoir of the virus. The viral particle contains a lipid envelope with fusion (F) and hemagglutinin (H) glycoproteins that mediate attachment to and entry into host cells. Measles virus is one of the most contagious human pathogens known and is transmitted primarily through respiratory droplets and airborne aerosols. Following infection, the virus initially replicates in the respiratory tract and regional lymphoid tissues before disseminating systemically. Measles virus can induce transient but profound immune suppression, increasing susceptibility to secondary infections for weeks to months after recovery. Widespread vaccination has dramatically reduced disease incidence in many regions, although outbreaks continue to occur where vaccination coverage is insufficient.

Diagnosis
The diagnosis of measles virus infection is performed through serological and molecular methods. Detection of measles-specific IgM antibodies by ELISA is commonly used to confirm recent infection, while IgG antibody testing may be used to assess immune status or evidence of prior exposure. Reverse transcription polymerase chain reaction (RT-PCR) provides highly sensitive detection of viral RNA in respiratory specimens, throat swabs, nasopharyngeal samples, urine, and blood and is particularly useful during the early phase of infection. Viral genotyping may be performed for epidemiological investigations and outbreak surveillance. Laboratory confirmation is important because clinical symptoms can resemble those of other viral exanthematous illnesses.

Symptoms
Measles virus infection typically develops following an incubation period of approximately seven to fourteen days. Early symptoms include high fever, cough, coryza (runny nose), conjunctivitis, malaise, and characteristic Koplik spots on the oral mucosa. Several days later, a maculopapular rash appears, beginning on the face and spreading downward to the trunk and extremities. Additional symptoms may include headache, fatigue, loss of appetite, and lymphadenopathy. Although most individuals recover completely, severe complications can occur, particularly in young children, malnourished individuals, pregnant women, and immunocompromised patients. Complications include otitis media, pneumonia, diarrhea, encephalitis, and the rare but fatal neurological disorder subacute sclerosing panencephalitis (SSPE). Measles remains a significant cause of vaccine-preventable morbidity and mortality worldwide.

Data

FAQ & Publications

Frequently Asked Questions

What type of samples can be used with the Measles Virus IgM ELISA Kit ESR102M?

The kit is compatible with serum, plasma, and whole blood samples for the detection of Measles Virus IgM antibodies.

Why is RF-Absorbent Z200 recommended for use with this IgM ELISA kit?

RF-Absorbent Z200 is recommended to remove IgM rheumatoid factors from serum and plasma samples prior to testing, which helps to eliminate false negative results and improve signal specificity.

How should the Measles Virus IgM ELISA Kit ESR102M be stored to maintain stability?

The kit components should be stored refrigerated at 2-8°C to preserve their activity and ensure reliable assay performance.

What is the assay format and detection type employed by this Measles Virus IgM ELISA kit?

This is an indirect and quantitative ELISA designed to detect human antibodies specific to Measles Virus IgM.

Is the Measles Virus IgM ELISA Kit ESR102M suitable for detecting acute measles infections?

Yes, the kit is specifically recommended for the determination of acute measles virus infections by detecting IgM antibodies.

Publications

pmid	title	authors	citation
38627149	Measles outbreak associated with a preschool setting among partially vaccinated children in the Tel Aviv District, Israel, October 2023.	Rivka Sheffer, Efrat Bucris, Ziva Amitai, Victoria Indenbaum, Yaniv Lustig, Michal Savion, Naama Nuss, Shepherd Roee Singer, Sharon Alroy Preis, Sharon Almagor, Eyal Leshem, Matanelle Salama	Vaccine 42:3153-3156
38275299	Diagnostic accuracy of commercially available serological tests for the detection of measles and rubella viruses: a systematic review and meta-analysis.	Vanessa Zubach, Jennifer Beirnes, Shannon Hayes, Alberto Severini, Joanne Hiebert	J Clin Microbiol 62:e0133923
36409098	Performance Characteristics of Six Immunoglobulin M Enzyme-Linked Immunosorbent Assays Used for Laboratory Confirmation of Measles.	Sun B Sowers, Kiana Anthony, Sara Mercader, Heather Colley, Stephen N Crooke, Paul A Rota, Donald R Latner, Carole J Hickman	J Clin Microbiol 60:e0122722
34705533	Evaluation of Diagnostic Accuracy of Eight Commercial Assays for the Detection of Rubella Virus-Specific IgM Antibodies.	Joanne Hiebert, Vanessa Zubach, Carmen L Charlton, Jayne Fenton, Graham A Tipples, Kevin Fonseca, Alberto Severini	J Clin Microbiol 60:e0159721
31377078	Study on factors associated with seroprotection after measles vaccination in children of 6-14 years in Eastern China.	Rui Yan, Hanqing He, Yang Zhou, Shuyun Xie, Xuan Deng, Xuewen Tang	Vaccine 37:5185-5190

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
ESR102M protocol

Documents

#
EP0036	Safety Data Sheet	QC certificate
EQ0064	Safety Data Sheet	QC certificate

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Measles Virus IgM ELISA kit-SERION classic ESR102M

RF-Absorbent Z200 for use with IgM ELISA kits

Data

FAQ & Publications

Protocols

Documents

Related Technical Resources & Posts

Reviews

Related Products

Measles Virus IgG ELISA kit-SERION classic ESR102G

Campylobacter jejuni IgG ELISA Kit MD-6204

Adenovirus IgG ELISA kit-SERION classic ESR128G

Aspergillus fumigatus IgA ELISA kit-SERION classic ESR132A

Hepatitis E (HEV) IgM ELISA Kit MD-5005

Bordetella pertussis IgM ELISA kit-SERION classic ESR120M

Hepatitis E (HEV) IgG ELISA Kit MD-5004

Aspergillus fumigatus IgM ELISA kit-SERION classic ESR132M

SARS-CoV-2 IgA ELISA Kit MD-7305

SARS-CoV-2 IgG ELISA Kit MD-7304

Aspergillus fumigatus IgG ELISA kit-SERION classic ESR132G

Adenovirus IgA ELISA kit-SERION classic ESR128A

Measles Virus IgM ELISA Kit control serum BC102M

Measles Virus IgG ELISA Kit Control serum BC102G

Campylobacter jejuni IgA ELISA Kit MD-6205