| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| target | Mycoplasma pneumoniae P1 |
| species reactivity | Mycoplasma pneumoniae |
| applications | ELISA |
| assay type | Indirect & quantitative |
| available size | 1 mg |
Mycoplasma pneumoniae P1 Antigen BA127VSP1
$1,168.00
Summary
- Virion/Serion Immunologics Antigen for research use (RUO)
- Mycoplasma pneumoniae P1 Antigen, recombinant
- Suitable for detection of IgA, IgG & IgM antibodies in ELISA
- Lot specific concentration, specified in mg/mL
- 1 mg
Mycoplasma pneumoniae P1 Antigen BA127VSP1
| kit |
|---|
| Research area Infectious Disease |
| Storage Store at -65°C or lower. Avoid repeated freeze-thaw cycles. 10 years from date of manufacture (under recommended storage conditions). |
| Form liquid |
| Associated products Mycoplasma pneumoniae Antigen (BA127VS) Mycoplasma pneumoniae P1 Antigen (BA127VSP1) Mycoplasma pneumoniae IgA Control Serum (BC127A) Mycoplasma pneumoniae IgG Control Serum (BC127G) Mycoplasma pneumoniae IgM Control Serum (BC127M) Mycoplasma pneumoniae IgA ELISA Kit (ESR127A) Mycoplasma pneumoniae IgG ELISA Kit (ESR127G) Mycoplasma pneumoniae IgM ELISA Kit (ESR127M) |
| target relevance |
|---|
| Mycoplasma pneumoniae |
| Description Bacterium that causes atypical pneumonia and respiratory tract infections |
| Structure Mycoplasma pneumoniae is a small, self-replicating bacterium belonging to the family Mycoplasmataceae. Unlike most bacteria, M. pneumoniae lacks a cell wall and is instead surrounded by a sterol-containing cell membrane, making it naturally resistant to beta-lactam antibiotics such as penicillins and cephalosporins. The organism is highly specialized for colonization of the human respiratory tract, where it attaches to ciliated epithelial cells using a specialized attachment organelle. Mycoplasma pneumoniae is one of the smallest free-living organisms capable of independent replication and possesses a highly reduced genome reflecting its dependence on host-derived nutrients. The bacterium is transmitted through respiratory droplets and is a common cause of community-acquired respiratory infections worldwide, particularly among school-aged children, adolescents, and young adults. |
| Diagnosis The diagnosis of Mycoplasma pneumoniae infection is performed through molecular, serological, and microbiological methods. Polymerase chain reaction (PCR) assays are considered the most sensitive and specific diagnostic tools and allow rapid detection of M. pneumoniae DNA from respiratory specimens. Serological assays, including ELISA-based tests, are commonly used to detect Mycoplasma-specific IgM and IgG antibodies and may assist in the diagnosis of acute or recent infection. Culture of M. pneumoniae is possible using specialized media but is rarely performed in routine clinical practice due to slow growth and technical complexity. Chest radiography may reveal diffuse or patchy infiltrates that are often disproportionate to the severity of clinical symptoms. Laboratory confirmation is particularly useful because clinical findings frequently overlap with those of viral respiratory infections. |
| Symptoms Mycoplasma pneumoniae infection typically develops following an incubation period of approximately one to four weeks. Common symptoms include persistent dry cough, sore throat, fever, headache, fatigue, and malaise. Respiratory illness often begins gradually and may progress from upper respiratory tract infection to atypical pneumonia characterized by prolonged cough and diffuse pulmonary involvement. Many patients remain ambulatory despite radiographic evidence of pneumonia, leading to the term 'walking pneumonia.' Extrapulmonary manifestations may occur and can include skin rashes, hemolytic anemia, myocarditis, pericarditis, hepatitis, arthritis, and neurological complications such as encephalitis or Guillain-Barré syndrome. Although most infections are self-limiting, severe disease may occur in immunocompromised individuals and patients with underlying respiratory conditions. |
Data
FAQ & Publications
Frequently Asked Questions
What is the primary application of the Mycoplasma pneumoniae P1 Antigen BA127VSP1?
The Mycoplasma pneumoniae P1 Antigen BA127VSP1 is primarily used for ELISA assays to detect IgA, IgG, and IgM antibodies.
How should the Mycoplasma pneumoniae P1 Antigen BA127VSP1 be stored to maintain stability?
This antigen should be stored at -65°C or lower and should be protected from repeated freeze-thaw cycles to ensure stability for up to 10 years from the date of manufacture under recommended conditions.
Which species does the Mycoplasma pneumoniae P1 Antigen BA127VSP1 specifically react with?
The antigen is reactive specifically with Mycoplasma pneumoniae species.
Is the concentration of the Mycoplasma pneumoniae P1 Antigen BA127VSP1 consistent across lots?
The concentration is lot-specific and is specified in milligrams per milliliter for each batch.
Can the Mycoplasma pneumoniae P1 Antigen BA127VSP1 be used for quantitative measurement in assays?
Yes, it is suitable for indirect and quantitative ELISA assays to detect antibody responses.
Publications
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| We haven't added any publications to our database yet. | |||
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.
Protocols
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