Mycoplasma pneumoniae Antigen BA127VS

$1,150.00

Summary

Virion/Serion Immunologics Antigen for research use (RUO)
Mycoplasma pneumoniae Antigen, recombinant
Suitable for detection of IgA, IgG & IgM antibodies in ELISA
Lot specific concentration, specified in mg/mL
1 mg

SKU: BA127VS Category: Infectious disease proteins Tags: antigen, Mycoplasma pneumoniae, protein

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Mycoplasma pneumoniae
species reactivity	Mycoplasma pneumoniae
applications	ELISA
assay type	Indirect & quantitative
available size	1 mg

Mycoplasma pneumoniae Antigen BA127VS

kit
Research area Infectious Disease
Storage Store at -65°C or lower. Avoid repeated freeze-thaw cycles. Sonicate before use. 10 years from date of manufacture (under recommended storage conditions).
Form liquid
Associated products Mycoplasma pneumoniae Antigen (BA127VS) Mycoplasma pneumoniae P1 Antigen (BA127VSP1) Mycoplasma pneumoniae IgA Control Serum (BC127A) Mycoplasma pneumoniae IgG Control Serum (BC127G) Mycoplasma pneumoniae IgM Control Serum (BC127M) Mycoplasma pneumoniae IgA ELISA Kit (ESR127A) Mycoplasma pneumoniae IgG ELISA Kit (ESR127G) Mycoplasma pneumoniae IgM ELISA Kit (ESR127M)

target relevance
Mycoplasma pneumoniae
Description Bacterium that causes atypical pneumonia and respiratory tract infections
Structure Mycoplasma pneumoniae is a small, self-replicating bacterium belonging to the family Mycoplasmataceae. Unlike most bacteria, M. pneumoniae lacks a cell wall and is instead surrounded by a sterol-containing cell membrane, making it naturally resistant to beta-lactam antibiotics such as penicillins and cephalosporins. The organism is highly specialized for colonization of the human respiratory tract, where it attaches to ciliated epithelial cells using a specialized attachment organelle. Mycoplasma pneumoniae is one of the smallest free-living organisms capable of independent replication and possesses a highly reduced genome reflecting its dependence on host-derived nutrients. The bacterium is transmitted through respiratory droplets and is a common cause of community-acquired respiratory infections worldwide, particularly among school-aged children, adolescents, and young adults.
Diagnosis The diagnosis of Mycoplasma pneumoniae infection is performed through molecular, serological, and microbiological methods. Polymerase chain reaction (PCR) assays are considered the most sensitive and specific diagnostic tools and allow rapid detection of M. pneumoniae DNA from respiratory specimens. Serological assays, including ELISA-based tests, are commonly used to detect Mycoplasma-specific IgM and IgG antibodies and may assist in the diagnosis of acute or recent infection. Culture of M. pneumoniae is possible using specialized media but is rarely performed in routine clinical practice due to slow growth and technical complexity. Chest radiography may reveal diffuse or patchy infiltrates that are often disproportionate to the severity of clinical symptoms. Laboratory confirmation is particularly useful because clinical findings frequently overlap with those of viral respiratory infections.
Symptoms Mycoplasma pneumoniae infection typically develops following an incubation period of approximately one to four weeks. Common symptoms include persistent dry cough, sore throat, fever, headache, fatigue, and malaise. Respiratory illness often begins gradually and may progress from upper respiratory tract infection to atypical pneumonia characterized by prolonged cough and diffuse pulmonary involvement. Many patients remain ambulatory despite radiographic evidence of pneumonia, leading to the term 'walking pneumonia.' Extrapulmonary manifestations may occur and can include skin rashes, hemolytic anemia, myocarditis, pericarditis, hepatitis, arthritis, and neurological complications such as encephalitis or Guillain-Barré syndrome. Although most infections are self-limiting, severe disease may occur in immunocompromised individuals and patients with underlying respiratory conditions.

Data

FAQ & Publications

Frequently Asked Questions

What is the primary application of the Mycoplasma pneumoniae Antigen BA127VS?

The Mycoplasma pneumoniae Antigen BA127VS is primarily used for the detection of IgA, IgG, and IgM antibodies in ELISA assays, enabling indirect and quantitative analysis.

How should the Mycoplasma pneumoniae Antigen BA127VS be stored to maintain stability?

This antigen should be stored at -65°C or lower, avoiding repeated freeze-thaw cycles. For use, it is recommended to sonicate the antigen before application. Under these conditions, the antigen is stable for up to 10 years from the date of manufacture.

Is the Mycoplasma pneumoniae Antigen BA127VS compatible with different immunoglobulin classes for antibody detection?

Yes, the antigen is suitable for detecting multiple immunoglobulin classes, specifically IgA, IgG, and IgM antibodies, in ELISA formats.

What is the species specificity of the Mycoplasma pneumoniae Antigen BA127VS?

The antigen is reactive specifically with Mycoplasma pneumoniae, the target organism for this product.

What is the form and concentration details provided for the Mycoplasma pneumoniae Antigen BA127VS?

The antigen is supplied in liquid form with a lot-specific concentration specified in mg/mL. The available size for purchase is 1 mg.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.