Chlamydia trachomatis IgA Control Serum BC1372A

$94.00

Summary

Virion/Serion Diagnostic Kit Control for research use (RUO)
Chlamydia trachomatis IgA Control Serum
Applications: ELISA
IgA control serum
Ready-to-use; pre-diluted for SERION ELISA classic and SERION ELISA antigen assays
3 mL

SKU: BC1372A Categories: control serum, Virion/Serion kits Tags: Chlamydia, ELISA control serum, IgA

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Chlamydia trachomatis reactive IgA
species reactivity	Chlamydia trachomatis
applications	ELISA
assay type	Indirect & quantitative
available size	3 mL

Chlamydia trachomatis IgA Control Serum BC1372A

kit
Research area Infectious Disease
Storage Store at 2-8°C.
Associated products Chlamydia trachomatis EB + RB Antigen (BA1372VSER) Chlamydia trachomatis MOMP Antigen (BA1372VSR2) Chlamydia trachomatis IgA Control Serum (BC1372A) Chlamydia trachomatis IgG Control Serum (BC1372G) Chlamydia trachomatis IgM Control Serum (BC1372M) Chlamydia trachomatis IgA ELISA Kit (ESR1372A) Chlamydia trachomatis IgG ELISA Kit (ESR1372G) Chlamydia trachomatis IgM ELISA Kit (ESR1372M) Chlamydia IgA ELISA Kit (ESR137A)

target relevance

human antibody anti-Chlamydia trachomatis

Chlamydia trachomatis

Description
Bacterium that causes chlamydial sexually transmitted infections, trachoma, and lymphogranuloma venereum

Structure
Chlamydia trachomatis is an obligate intracellular Gram-negative bacterium belonging to the family Chlamydiaceae. The organism possesses a unique biphasic developmental cycle consisting of the infectious elementary body (EB) and the metabolically active reticulate body (RB). Elementary bodies are specialized for extracellular survival and host cell infection, while reticulate bodies replicate within membrane-bound intracellular inclusions inside host epithelial cells. Chlamydia trachomatis is a strictly human pathogen and is one of the most common bacterial causes of sexually transmitted infections worldwide. Different serovars are associated with distinct diseases, including urogenital infections, trachoma, and lymphogranuloma venereum (LGV). Because the organism relies extensively on host cellular machinery for replication, it cannot be propagated on conventional bacteriological culture media.

Diagnosis
The diagnosis of Chlamydia trachomatis infection is performed primarily through nucleic acid amplification tests (NAATs), including polymerase chain reaction (PCR)-based assays, which are considered the gold standard due to their high sensitivity and specificity. Testing can be performed using urine specimens, vaginal swabs, cervical swabs, urethral swabs, rectal swabs, or other appropriate clinical samples. Serological assays, including ELISA-based methods, may be useful for epidemiological studies or selected clinical situations but are generally less useful for diagnosing uncomplicated genital infections. Culture techniques are rarely used in routine clinical practice because of technical complexity. Early and accurate diagnosis is essential because many infections are asymptomatic and untreated disease can result in significant long-term complications.

Symptoms
Chlamydia trachomatis infection is frequently asymptomatic, particularly in women, which contributes to ongoing transmission. Symptomatic urogenital infection may present with dysuria, urethral discharge, cervicitis, abnormal vaginal discharge, pelvic pain, postcoital bleeding, or testicular pain. Untreated infection can ascend to cause pelvic inflammatory disease (PID), ectopic pregnancy, infertility, and chronic pelvic pain. Certain serovars cause lymphogranuloma venereum, characterized by genital ulcers followed by painful lymphadenopathy and proctocolitis. Ocular infection can result in trachoma, a chronic inflammatory eye disease that remains a leading infectious cause of blindness worldwide. Neonatal infection acquired during childbirth may cause conjunctivitis or pneumonia. Prompt diagnosis and treatment are important to prevent complications and reduce transmission.

Data

FAQ & Publications

Frequently Asked Questions

What is the primary application of the Chlamydia trachomatis IgA Control Serum BC1372A?

The Chlamydia trachomatis IgA Control Serum BC1372A is primarily used as a control serum for ELISA assays to detect IgA antibodies reactive to Chlamydia trachomatis.

How should the Chlamydia trachomatis IgA Control Serum BC1372A be stored to maintain its stability?

The serum should be stored at 2-8°C to ensure proper stability and functionality.

Is the Chlamydia trachomatis IgA Control Serum BC1372A ready to use or does it require dilution before application?

This control serum is supplied ready-to-use and pre-diluted specifically for use with SERION ELISA classic and SERION ELISA antigen assays.

Which species reactivity is confirmed for the Chlamydia trachomatis IgA Control Serum BC1372A?

The serum is reactive specifically to Chlamydia trachomatis species.

What type of assay format is the Chlamydia trachomatis IgA Control Serum BC1372A validated for?

It is validated for indirect and quantitative ELISA assay formats.

Publications

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We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
BC1372A protocol

Documents

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Chlamydia trachomatis IgA Control Serum BC1372A

Data

FAQ & Publications

Protocols

Documents

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Reviews

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