Brucella IgA Control Serum BC116A

$94.00

Summary

Virion/Serion Diagnostic Kit Control for research use (RUO)
Brucella IgA Control Serum
Applications: ELISA
IgA control serum
Ready-to-use; pre-diluted for SERION ELISA classic and SERION ELISA antigen assays
3 mL

SKU: BC116A Categories: control serum, Virion/Serion kits Tags: Brucella, ELISA control serum, IgA

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Brucella reactive IgA
species reactivity	Brucella
applications	ELISA
assay type	Indirect & quantitative
available size	3 mL

Brucella IgA Control Serum BC116A

kit
Research area Infectious Disease
Storage Store at 2-8°C.
Associated products Brucella abortus Antigen (BA116VS) Brucella IgA Control Serum (BC116A) Brucella IgG Control Serum (BC116G) Brucella IgM Control Serum (BC116M) Brucella IgA ELISA Kit (ESR116A) Brucella IgG ELISA Kit (ESR116G) Brucella IgM ELISA Kit (ESR116M)

target relevance

human antibody anti-Brucella

Brucella

Description
Bacterial genus that causes brucellosis (undulant fever)

Structure
Brucella is a genus of small, Gram-negative, facultative intracellular coccobacilli belonging to the family Brucellaceae. Members of the genus are zoonotic pathogens that infect a wide range of domestic and wild animals, including cattle, sheep, goats, pigs, dogs, and wildlife species. The most important human pathogens include Brucella melitensis, Brucella abortus, Brucella suis, and Brucella canis. Brucella species are highly adapted to survival and replication within macrophages and other phagocytic cells, enabling persistent infection and evasion of host immune responses. Transmission to humans commonly occurs through direct contact with infected animals, inhalation of contaminated aerosols, or consumption of unpasteurized dairy products. Due to their low infectious dose and ability to become aerosolized, Brucella species are considered important laboratory-acquired pathogens.

Diagnosis
The diagnosis of brucellosis is performed through microbiological, serological, and molecular methods. Isolation of Brucella organisms from blood, bone marrow, or tissue specimens remains the definitive diagnostic method, although culture may require prolonged incubation and specialized laboratory precautions. Serological testing is widely used and includes standard agglutination tests, ELISA, complement fixation tests, and other assays for the detection of Brucella-specific antibodies. Polymerase chain reaction (PCR) provides rapid and sensitive detection of Brucella DNA and may be particularly useful in chronic or complicated cases. Laboratory findings often include anemia, leukopenia, thrombocytopenia, and elevated inflammatory markers. Because symptoms are frequently nonspecific, laboratory confirmation is essential for diagnosis.

Symptoms
Brucellosis typically develops following an incubation period of one to four weeks but may occur months after exposure. The disease is characterized by fever, chills, profuse night sweats, fatigue, malaise, headache, muscle aches, joint pain, and loss of appetite. Fever may follow a recurrent or undulating pattern, giving rise to the term 'undulant fever.' Chronic infection can involve multiple organ systems and may result in arthritis, spondylitis, osteomyelitis, epididymo-orchitis, hepatitis, endocarditis, and neurological complications. Endocarditis is the most serious complication and is the leading cause of brucellosis-associated mortality. Without appropriate treatment, symptoms may persist for months or years and can cause significant long-term disability.

Data

FAQ & Publications

Frequently Asked Questions

What is the intended application of the Brucella IgA Control Serum BC116A?

The Brucella IgA Control Serum BC116A is designed for use as a control serum in ELISA applications, specifically for the detection of Brucella reactive IgA antibodies.

How should the Brucella IgA Control Serum BC116A be stored to maintain stability?

This control serum should be stored refrigerated at 2-8°C to preserve its integrity and functionality.

Is the Brucella IgA Control Serum BC116A compatible with SERION ELISA kits?

Yes, the serum is ready-to-use and pre-diluted for compatibility with SERION ELISA classic and SERION ELISA antigen assays.

What type of assay format does the Brucella IgA Control Serum BC116A support?

The serum supports indirect and quantitative ELISA assay formats for the detection of Brucella IgA antibodies.

Publications

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We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
BC116A protocol

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Brucella IgA Control Serum BC116A

Data

FAQ & Publications

Protocols

Documents

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