| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| target | Candida albicans reactive IgM |
| species reactivity | Candida albicans |
| applications | ELISA |
| assay type | Indirect & quantitative |
| available size | 3 mL |
Candida albicans IgM Control Serum BC117M
$94.00
Summary
- Virion/Serion Diagnostic Kit Control for research use (RUO)
- Candida albicans IgM Control Serum
- Applications: ELISA
- IgM control serum
- Ready-to-use; pre-diluted for SERION ELISA classic and SERION ELISA antigen assays
- 3 mL
Candida albicans IgM Control Serum BC117M
| target relevance |
|---|
| Candida albicans |
| Description Fungus that causes candidiasis and opportunistic fungal infections |
| Structure Candida albicans is a dimorphic yeast-like fungus belonging to the family Debaryomycetaceae and is the most common cause of human candidiasis. The organism normally colonizes the oral cavity, gastrointestinal tract, genitourinary tract, and skin of healthy individuals as part of the normal microbiota. Candida albicans exhibits remarkable morphological flexibility and can transition between yeast, pseudohyphal, and true hyphal forms depending on environmental conditions. This ability to undergo morphologic switching is an important virulence factor that facilitates tissue invasion, immune evasion, and biofilm formation. C. albicans is an opportunistic pathogen that typically causes disease when host defenses are compromised, microbiota balance is disrupted, or anatomical barriers are breached. It is one of the most common fungal pathogens responsible for both superficial mucosal infections and invasive systemic disease. |
| Diagnosis The diagnosis of Candida albicans infection is performed through microbiological, microscopic, molecular, and serological methods. Direct microscopic examination of clinical specimens using potassium hydroxide preparations, Gram staining, or fungal stains may reveal budding yeast cells, pseudohyphae, and hyphae. Culture on fungal media remains a standard diagnostic method and allows species identification and antifungal susceptibility testing. Molecular techniques such as polymerase chain reaction (PCR) provide rapid and sensitive detection of Candida DNA. In cases of invasive candidiasis, blood cultures, beta-D-glucan assays, antigen detection tests, and advanced molecular diagnostics may assist in diagnosis. Histopathological examination of affected tissues can demonstrate fungal invasion and support the diagnosis of invasive disease. |
| Symptoms Candida albicans infections range from mild superficial disease to life-threatening systemic infections. Oral candidiasis (thrush) commonly presents with white plaques on the tongue and oral mucosa, soreness, and difficulty swallowing. Vulvovaginal candidiasis is characterized by itching, irritation, redness, burning, and abnormal vaginal discharge. Cutaneous candidiasis may cause erythematous, moist, and pruritic lesions, particularly in warm skin folds. Invasive candidiasis occurs when the organism enters the bloodstream or deep tissues and may present with persistent fever, chills, sepsis, organ dysfunction, and failure to respond to antibacterial therapy. Patients at highest risk include immunocompromised individuals, transplant recipients, cancer patients, premature infants, and critically ill hospitalized patients. Untreated invasive infection may disseminate to the kidneys, liver, spleen, heart, eyes, brain, and other organs, resulting in significant morbidity and mortality. |
Data
FAQ & Publications
Frequently Asked Questions
What is the intended application for the Candida albicans IgM Control Serum BC117M?
The Candida albicans IgM Control Serum BC117M is designed for use in ELISA assays, specifically for indirect and quantitative detection of IgM antibodies reactive to Candida albicans.
How should the Candida albicans IgM Control Serum BC117M be stored to maintain its stability?
This control serum should be stored at 2-8°C to preserve its integrity and ensure reliable assay performance.
Is the Candida albicans IgM Control Serum BC117M ready to use or does it require dilution before application?
The serum is provided ready-to-use and pre-diluted for compatibility with SERION ELISA classic and SERION ELISA antigen assays.
Which species' antibodies does the Candida albicans IgM Control Serum BC117M specifically target?
This control serum targets IgM antibodies reactive to Candida albicans, a pathogenic yeast species relevant in infectious disease research.
Can the Candida albicans IgM Control Serum BC117M be used to monitor therapy or infection in patients?
While this serum serves as a control in ELISA assays for Candida albicans IgM detection, serological diagnosis of candidiasis requires multiple methods for accurate interpretation, as antibody responses can vary in different clinical conditions.
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.
Protocols
| relevant to this product |
|---|
| BC117M protocol |
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