Weight | 1 lbs |
---|---|
Dimensions | 9 × 5 × 2 in |
host | mouse |
isotype | IgG |
clonality | monoclonal |
concentration | concentrate, predilute |
applications | IHC |
reactivity | human |
available size | 0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted |
rabbit anti-STAT6 monoclonal antibody (ZR289) 6369
$160.00 – $528.00
Antibody summary
- Rabbit monoclonal to STAT6
- Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
- Reacts with: Human
- Isotype:IgG
- Control: Solitary fibrous tumor
- Visualization: Nuclear
- 0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted
rabbit anti-STAT6 monoclonal antibody ZR289 6369
target relevance |
---|
Protein names Signal transducer and activator of transcription 6 (IL-4 Stat) |
Gene names STAT6,STAT6 |
Protein family Transcription factor STAT family |
Mass 94135Da |
Function Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling. |
Subellular location Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation. |
Structure Forms a homodimer or a heterodimer with a related family member (By similarity). Interacts with NCOA1 via its C-terminal LXXLL motif. |
Post-translational modification Tyrosine phosphorylated on Tyr-641 following stimulation by IL4/interleukin-4 (PubMed:27796300). Tyrosine phosphorylated following stimulation by IL3/interleukin-3 (By similarity). Dephosphorylation on tyrosine residues by PTPN2 negatively regulates the IL4/interleukin-4 mediated signaling (PubMed:17210636).; Mono-ADP-ribosylated by PARP14. |
Target Relevance information above includes information from UniProt accession: P42226 |
The UniProt Consortium |
Data
Formalin-fixed, paraffin-embedded human solitary fibrous tumor stained with anti-STAT6 antibody using peroxidase-conjugate and DAB chromogen. Note nuclear and cytoplasmic staining of tumor cells |
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.pmid | title | authors | citation |
---|
Protocols
relevant to this product |
---|
IHC |
Documents
# | |||
---|---|---|---|
Please enter your product and batch number here to retrieve - product datasheet, SDS, and QC information. |
Only logged in customers who have purchased this product may leave a review.
Reviews
There are no reviews yet.