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mouse anti-NKX2.2 monoclonal antibody (ZM14) 6289

$160.00$528.00

Antibody summary

  • Mouse monoclonal to NKX2.2
  • Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
  • Reacts with: Human
  • Isotype:IgG1
  • Control: Ewing’s sarcoma
  • Visualization: Nuclear
  • 0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted
SKU: 6289parent Category: Tags: , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
host

mouse

isotype

IgG1

clonality

monoclonal

concentration

concentrate, predilute

applications

IHC

reactivity

human

available size

0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

mouse anti-NKX2.2 monoclonal antibody ZM14 6289

antibody
Database link:
human O95096
Tested applications
IHC
Recommended dilutions
As directed
Immunogen
Human recombinant NKX2.2 protein fragment (aa 1-119)
Size and concentration
7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form
liquid
Storage Instructions
2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity
affinity purified
Clonality
monoclonal
Isotype
IgG1
Compatible secondaries
goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486
goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685
goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854
goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706
goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716
goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control
Mouse monoclonal IgG1 - Isotype Control
target relevance
Protein names
Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B)
Protein family
NK-2 homeobox family
Mass
30133Da
Function
Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (By similarity). May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter (By similarity). .
Subellular location
Nucleus .
Structure
Interacts with OLIG2. .
Target Relevance information above includes information from UniProt accession: O95096
The UniProt Consortium

Data

Human Ewing'ss sarcoma stained with anti-NKX2.2 antibody using peroxidase-conjugate and DAB chromogen. Note nuclear staining of tumor cells.
Human Ewing'ss sarcoma stained with anti-NKX2.2 antibody using peroxidase-conjugate and DAB chromogen. Note nuclear staining of tumor cells.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




pmidtitleauthorscitation

Protocols

relevant to this product
IHC

Documents

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