Immunohistochemistry (IHC) : Human lymph node stained with anti-Lysozyme antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of perifollicular neutrophils and histiocytes..

mouse anti-Lysozyme monoclonal antibody (ZM120) 6244

$160.00 – $528.00

Antibody summary

Mouse monoclonal to Lysozyme
Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Reacts with: Human
Isotype:IgG2b
Control: Myeloid leukemia
Visualization: Cytoplasmic
0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted

SKU: 6244parent Category: antibody Tags: anatomy, Hematopathology, Lysozyme

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgG2b
clonality	monoclonal
concentration	concentrate, predilute
applications	IHC
reactivity	human
available size	0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

mouse anti-Lysozyme monoclonal antibody ZM120 6244

antibody
Database link: human P61626
Tested applications IHC
Recommended dilutions Concentrated 1:100-200
Applicaiton Notes Positive control: Myeloid leukemia
Immunogen Recombinant fragment of human Lysozyme protein (around aa 18-147)
Size and concentration 7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form liquid
Storage Instructions 2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity affinity purified
Clonality monoclonal
Isotype IgG2b
Compatible secondaries goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486 goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854 goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706 goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control Mouse monoclonal IgG2b - Isotype Control

target relevance
Protein names Lysozyme C (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase C)
Protein family Glycosyl hydrolase 22 family
Mass 16537Da
Function Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
Catalytic activity CATALYTIC ACTIVITY: Reaction=Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.; EC=3.2.1.17;
Subellular location Secreted.
Structure Monomer.
Domain DOMAIN 19..148; /note="C-type lysozyme"; /evidence="ECO:0000255\|PROSITE-ProRule:PRU00680"
Involvement in disease Amyloidosis 8 (AMYL8) [MIM:105200]: A form of hereditary generalized amyloidosis. Clinical features include extensive visceral amyloid deposits, renal amyloidosis resulting in nephrotic syndrome, arterial hypertension, hepatosplenomegaly, cholestasis, petechial skin rash. There is no involvement of the nervous system. Note=The disease is caused by variants affecting the gene represented in this entry.
Target Relevance information above includes information from UniProt accession: P61626
The UniProt Consortium

Data

Human lymph node stained with anti-Lysozyme antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of perifollicular neutrophils and histiocytes..

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.