Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
host | rabbit |
isotype | IgG |
clonality | polyclonal |
concentration | serum |
applications | ICC/IF, IHC, WB |
reactivity | modified proteins |
available sizes | 1 mL, 100 µL, 25 µL |
rabbit anti-Ubiquitin polyclonal antibody 5775
$100.00 – $2,600.00
Antibody summary
- Rabbit polyclonal to Ubiquitin
- Suitable for: WB, ICC/IF, IHC
- Reacts with: all
- Isotype: IgG
- 100 µL, 25 µL, 1 mL
rabbit anti-Ubiquitin polyclonal antibody 5775
antibody |
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Database link: Ubiquitin Sequence - MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG |
Tested applications WB,IHC,IHC,ICC/IF |
Recommended dilutions WB: 1:5000-1:10000 IF/ICC and IHC: 1:500-1:1000 |
Immunogen Purified ubiquitin conjugated with glutaraldehyde to KLH |
Size and concentration 25, 100, 1000µL and serum |
Form liquid |
Storage Instructions 2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles. |
Storage buffer serum, 0.04% NaN3 added |
Purity serum |
Clonality polyclonal |
Isotype IgG |
Compatible secondaries goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863 goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720 |
Isotype control Rabbit polyclonal - Isotype Control |
target relevance |
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Ubiquitin plays a fundamental role in cell biology as a key regulator of protein degradation and cellular processes. More on: cell markers and ubiquitin |
Biotechnology Ubiquitin, a small protein found in nearly all eukaryotic cells, plays a fundamental role in regulating various cellular processes. Its primary function is to mark proteins for degradation through the ubiquitin-proteasome system, a highly controlled and selective process known as ubiquitination. When a protein is destined for degradation or clearance, multiple ubiquitin molecules are covalently attached to specific lysine residues on the target protein, forming a polyubiquitin chain. This ubiquitin chain acts as a signal, directing the tagged protein to the proteasome, a large multi-subunit protein complex responsible for protein degradation. Once delivered to the proteasome, the ubiquitinated protein is unfolded and processed, and its constituent amino acids are recycled for the synthesis of new proteins. Apart from its role in protein degradation, ubiquitin also participates in various non-proteolytic functions, such as DNA repair, endocytosis, and signal transduction, where monoubiquitination or other ubiquitin modifications can serve as regulatory signals. The precise and intricate control of ubiquitin-mediated processes ensures proper cellular homeostasis, protein turnover, and the maintenance of critical cellular functions. |
Publications
pmid | title | authors | citation |
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We haven't added any publications to our database yet. |
relevant to this product |
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Western blot IHC ICC |
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